A new oxathiolane fromEnterobacter cloacae

Yap, A.C. and Teoh, W.Y. and Chan, Kok Gan and Sim, Kae Shin and Choo, Yeun Mun (2015) A new oxathiolane fromEnterobacter cloacae. Natural Product Research, 29 (8). pp. 722-726. ISSN 1478-6419, DOI https://doi.org/10.1080/14786419.2014.983507.

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Official URL: http://dx.doi.org/10.1080/14786419.2014.983507


Enterobacter cloacae is a versatile bacterial species inhabiting a wide variety of niches and is capable of metabolising a wide variety of substances as energy resources. The fermentation culture of this bacterial species has successfully yielded one new compound, Rimboxa (1) and three known compounds, i.e. indole-3-carboxaldehyde (2), indole-3-acetic acid (3) and 3,4-di-t-butylaniline (4). Rimboxa (1) is shown to possess the 1,2-oxathiolane core structure. 3,4-Di-t-butylaniline (4) is isolated for the first time from a natural resource. These compounds were isolated and characterised using extensive chromatographic and spectroscopic methods, and were subjected to cytotoxicity evaluations.

Item Type: Article
Funders: University of Malaya UMRG [grant number RG094/10AFR], [grant number RP002A-13Bio], University of Malaya HIR [grant number UM.C/625/1/HIR/043], Government of Malaysia MOSTI E-science fund [grant number SF004-2014], Postgraduate Research Fund of University Malaya [grant number PG027-2012B]
Uncontrolled Keywords: Enterobacter cloacae; Rimboxa; Oxathiolane; Spectroscopic analysis
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Q Science > QH Natural history
Divisions: Faculty of Science > Department of Chemistry
Faculty of Science > Institute of Biological Sciences
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 26 Sep 2018 01:33
Last Modified: 23 Dec 2019 02:27
URI: http://eprints.um.edu.my/id/eprint/19406

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