Helicobacter pylori and peptic ulcer disease--a causal link

Goh, Khean Lee (1997) Helicobacter pylori and peptic ulcer disease--a causal link. Medical Journal of Malaysia, 52 (2). pp. 161-168. ISSN 0300-5283, DOI 10968075.

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Official URL: http://www.e-mjm.org/1997/v52n2/Helicobacter_Pylor...


The link between Helicobacter. pylori and peptic ulcer disease in 1997 is an irrefutable one. The association between infection and ulcerogenesis has been shown to be biologically plausible with induction of epithelial inflammation and cell damage and its effect on gastrin/acid homeostasis. The association of H. pylori infection and peptic ulcer disease is a close and consistent one. There is ample evidence indicating that H. pylori eradication results in virtual abolition of ulcer relapse. Several studies have demonstrated that eradication of H. pylori results in ulcer healing and there is evidence showing a temporal relationship between infection and development of peptic ulcer disease.

Item Type: Article
Additional Information: Department of Medicine, University of Malaya
Uncontrolled Keywords: Gastric Acid/secretion; Helicobacter Infections/complications; Helicobacter Infections/drug therapy
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Mr. Faizal Hamzah
Date Deposited: 08 Jun 2011 01:47
Last Modified: 01 Mar 2019 06:02
URI: http://eprints.um.edu.my/id/eprint/1497

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