Molecular epidemiology of hepatitis C virus genotypes in Bushehr province, Iran

Vahdat, K. and Keyvani, H. and Tabib, S.M. and Rostamabadi, S. and Valizadeh, S.M. and Cheraghi, S. and Shamsian, S. and Zandi, K. (2010) Molecular epidemiology of hepatitis C virus genotypes in Bushehr province, Iran. European Review for Medical and Pharmacological Sciences, 14 (10). pp. 861-864.

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Background and Objectives: Molecular epidemiology of hepatitis C virus (HCV) is very important for the treatment of hepatitis C infection. The aim of this study was to determine the distribution of HCV genotypes in Bushehr province (South West of Iran). Materials and Methods: A total of 100 patients who were detected as positive for HCV antibody (by using ELISA method and RIBA test) referred to Arya Virology Laboratory between 2007-2009 in order to molecular diagnosis and furthermore virus genotyping. After detection of HCV, RNA genotyping of virus was done by using genotype specific primers. Results: Genotype 1a was found in 49% of the patients and genotype 3a was found in 40% of the patients and 1b in 5% of patients, while the genotype of the virus could not be identified in 5% of the patients. Finally, in 1% of patients coinfection due to 1a-3a genotypes was identified. Conclusion: The dominant genotype of HCV in Bushehr province, Iran, was determined as 1a.

Item Type: Article
Uncontrolled Keywords: Hepatitis C virus; Genotyping; RT-PCR; Bushehr; Iran
Subjects: R Medicine
Depositing User: Mr Faizal 2
Date Deposited: 20 Jan 2015 02:57
Last Modified: 20 Jan 2015 02:57

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