The risk and associated factors of methamphetamine psychosis in methamphetamine-dependent patients in Malaysia

Sulaiman, A.H. and Said, M.A. and Habil, M.H. and Rashid, R. and Siddiq, A. and Guan, N.C. and Midin, M. and Jaafar, N.R.N. and Sidi, H. and Das, S. (2014) The risk and associated factors of methamphetamine psychosis in methamphetamine-dependent patients in Malaysia. Comprehensive psychiatry, 55 (Supp. ). S89-S94. ISSN 0010-440X, DOI

Full text not available from this repository.
Official URL:


Objective: The objective of this study was to determine the risk of lifetime and current methamphetamine-induced psychosis in patients with methamphetamine dependence. The association between psychiatric co-morbidity and methamphetamine-induced psychosis was also studied. Methods: This was a cross-sectional study conducted concurrently at a teaching hospital and a drug rehabilitation center in Malaysia. Patients with the diagnosis of methamphetamine based on DSM-IV were interviewed using the Mini International Neuropsychiatric Interview (M.I.N.I.) for methamphetamine-induced psychosis and other Axis I psychiatric disorders. The information on sociodemographic background and drug use history was obtained from interview or medical records. Results: Of 292 subjects, 47.9 of the subjects had a past history of psychotic symptoms and 13.0 of the patients were having current psychotic symptoms. Co-morbid major depressive disorder (OR = 7.18, 95 CI = 2.612�19.708), bipolar disorder (OR = 13.807, 95 CI = 5.194�36.706), antisocial personality disorder (OR = 12.619, 95 CI = 6.702�23.759) and heavy methamphetamine uses were significantly associated with lifetime methamphetamine-induced psychosis after adjusted for other factors. Major depressive disorder (OR = 2.870, CI = 1.154�7.142) and antisocial personality disorder (OR = 3.299, 95 CI = 1.375�7.914) were the only factors associated with current psychosis. Conclusion: There was a high risk of psychosis in patients with methamphetamine dependence. It was associated with co-morbid affective disorder, antisocial personality, and heavy methamphetamine use. It is recommended that all cases of methamphetamine dependence should be screened for psychotic symptoms.

Item Type: Article
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms Haslinda Lahuddin
Date Deposited: 16 Jul 2014 01:56
Last Modified: 16 Jul 2014 01:56

Actions (login required)

View Item View Item