Intravenous salbutamol for external cephalic version

Vani, S. and Lau, S.Y. and Lim, B.K. and Omar, S.Z. and Tan, P.C. (2009) Intravenous salbutamol for external cephalic version. International Journal of Gynecology & Obstetrics, 104 (1). pp. 28-31. ISSN 0020-7292, DOI

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Objective: To evaluate the success of external cephalic version (ECV) using an adjusted bolus dose intravenous salbutamol compared with no tocolysis. Methods: An open-label randomized study of 114 women with a term breech fetus randomized to receive either an intravenous bolus dose of 0.1 mg salbutarnol with further boluses every 5 minutes, as required, before commencing ECV, or no tocolysis. Primary outcomes were successful ECV and rate of cesarean delivery. Results: Salbutamol tocolysis resulted in a higher rate of successful ECV compared with no tocolysis (70.2 40/57 vs 36.8% 21/57; RR 1.9, 95% CI 1.3-2.8; P<0.001). Cesarean delivery rate was lower in the salbutamol group compared with the control group (31.6% 18/57 vs 63.2% 36/57; RR 0.5. 95% CI 0.3-0.8: P=0.001). Salbutamol dose ranged from 0.1-0.4 mg and Outcome was not related to dose. Conclusion: Adjusted dose intravenous salbutamol tocolysis prior to ECV increases its success rate and reduces the cesarean delivery rate. (C) 2008 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

Item Type: Article
Uncontrolled Keywords: Cesarean delivery; Breech; External cephalic version; Salbutamol; Tocolysis
Subjects: R Medicine
R Medicine > RG Gynecology and obstetrics
Divisions: Faculty of Medicine
Depositing User: Ms Haslinda Lahuddin
Date Deposited: 16 Jul 2014 00:04
Last Modified: 16 Jul 2014 00:04

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