Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia

Chia, Y.C. and Ching, S.M. and Wan Ahmad, W.A. and Jalalian, M. (2012) Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia. Life Science Journal, 9 (3). pp. 713-719. ISSN 1097-8135,

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Heart failure in many patients is due to left Ventricular Diastolic Dysfunction (LVDD), but little is known about its prevalence among hypertensive adults, especially in the primary care setting. , This quantitative study aims to evaluate the prevalence and factors associated with LVDD. A cross-sectional study was conducted among 359 hypertensive patients who underwent echocardiography to define their cardiac structure and function. The peak ratio of early to late diastolic filling velocity was used to assess the LVDD. The Framingham Coronary Heart Disease risk score was derived from the most recent blood test available in the previous year. SPSS version 19 was used to analyze the data. Echocardiographic LVDD was found in 68% of the participants. Of the 243 hypertensive subjects who had LVDD, 69.5% did not have any left ventricular hypertrophy (LVH) while 30.5% had LVH. Age (odds ratio (OR) 1.11, 95% confidence interval (CI) 1.07-1.15), fasting blood glucose (OR 1.18, 95% CI 1.02-1.37), poor blood pressure control (OR 1.93, 95% CI 1.12-3.32), central obesity (OR 2.06, 95% CI 1.17-3.64), and LVH (OR 2.76, 95% CI 1.29- 5.90) were found to have a significant positive relation with LVDD. Poor hypertension control, diabetes, older age, central obesity, and LVH are the predictors for the development of diastolic dysfunction.

Item Type: Article
Additional Information: Department of Primary Care Medicine, Faculty of Medicine, University of Malaya
Uncontrolled Keywords: Prevalence; left ventricular diastolic dysfunction; hypertension; Malaysia
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine
Depositing User: Ms. Suhaila Syakila Alby
Date Deposited: 27 Oct 2014 01:45
Last Modified: 27 Oct 2014 01:45

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