Insecticide Resistance Development in Aedes aegypti upon Selection Pressure with Malathion

Hidayati, H. and Nazni, W.A. and Lee, H.L. and Sofian-Azirun, Mohd (2011) Insecticide Resistance Development in Aedes aegypti upon Selection Pressure with Malathion. Tropical Biomedicine, 28 (2). pp. 425-437. ISSN 0127-5720,

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Abstract

Bioassay test against malathion had been carried out with larval and adult stages of Aedes aegypti. The mosquitoes were under selection pressure against malathion for fortyfive consecutive generations. The rate of resistance development was measured by LC 50 and LT 50 values. The larvae and adult females, after subjection to malathion selection for 45 generations, developed high resistance level to malathion, with resistance ratio of 52.7 and 3.24 folds, respectively over control mosquitoes. Cross-resistance towards the same and different groups of insecticides was determined using the F44 and F45 malathion-selected adult females. Insecticides tested were DDT (4.0), permethrin (0.75), propoxur (0.1), fenitrothion (1), λ-cyhalothrin (0.05) and cyfluthrin (0.15). Results indicated that the mosquitoes were highly resistant to DDT and fenitrothion, moderately resistant to propoxur, tolerant to permethrin and λ-cyhalothrin, and very low resistant to cyfluthrin.

Item Type:	Article
Funders:	UNSPECIFIED
Uncontrolled Keywords:	insecticide malathion Aedes animal article bioassay drug effect female genetic selection insecticide resistance larva survival Animals Biological Assay Insecticides Selection, Genetic Survival Analysis
Subjects:	Q Science > QH Natural history > QH301 Biology
Divisions:	Faculty of Science > Institute of Biological Sciences
Depositing User:	miss munirah saadom
Date Deposited:	14 Jan 2013 02:46
Last Modified:	13 Feb 2019 09:12
URI:	http://eprints.um.edu.my/id/eprint/5807

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