Tan, Peng Chiong and Ramasandran, Gayaithiri and Sethi, Neha and Razali, Nuguelis and Hamdan, Mukhri and Kamarudin, Maherah (2023) Watermelon and dietary advice compared to dietary advice alone following hospitalization for hyperemesis gravidarum: a randomized controlled trial. BMC Pregnancy and Childbirth, 23 (1). ISSN 1471-2393, DOI https://doi.org/10.1186/s12884-023-05771-7.
Full text not available from this repository.Abstract
Background Hyperemesis gravidarum (HG) affects about 2% of pregnancies and is at the severe end of the spectrum of nausea and vomiting of pregnancy. HG causes severe maternal distress and results in adverse pregnancy outcomes long after the condition may have dissipated. Although dietary advice is a common tool in management, trial evidence to base the advice on is lacking. Methods A randomized trial was conducted in a university hospital from May 2019 to December 2020. 128 women at their discharge following hospitalization for HG were randomized: 64 to watermelon and 64 to control arm. Women were randomized to consume watermelon and to heed the advice leaflet or to heed the dietary advice leaflet alone. A personal weighing scale and a weighing protocol were provided to all participants to take home. Primary outcomes were bodyweight change at the end of week 1 and week 2 compared to hospital discharge. Results Weight change (kg) at end of week 1, medianinterquartile range] -0.05-0.775 to + 0.50] vs. -0.5-1.4 to + 0.1] P = 0.014 and to the end of week 2, + 0.25-0.65 to + 0.975] vs. -0.5-1.3 to + 0.2] P = 0.001 for watermelon and control arms respectively. After two weeks, HG symptoms assessed by PUQE-24 (Pregnancy-Unique Quantification of Emesis and Nausea over 24 h), appetite assessed by SNAQ (Simplified Nutritional Appetite Questionnaire), wellbeing and satisfaction with allocated intervention NRS (0-10 numerical rating scale) scores, and recommendation of allocated intervention to a friend rate were all significantly better in the watermelon arm. However, rehospitalization for HG and antiemetic usage were not significantly different. Conclusion Adding watermelon to the diet after hospital discharge for HG improves bodyweight, HG symptoms, appetite, wellbeing and satisfaction.
| Item Type: | Article |
|---|---|
| Funders: | Department of Obstetrics amp; Gynecology, Faculty of Medicine, Universiti Malaya |
| Uncontrolled Keywords: | Hyperemesis gravidarum; Nausea and vomiting of pregnancy; Watermelon; Appetite; Maternal satisfaction; Dietary advice |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RG Gynecology and obstetrics |
| Divisions: | Faculty of Medicine > Obstetrics & Gynaecology Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 30 Jul 2025 03:11 |
| Last Modified: | 30 Jul 2025 03:11 |
| URI: | http://eprints.um.edu.my/id/eprint/50747 |
Actions (login required)
 |
View Item |
