Lim, Lee-Ling and Aziz, Alia Abdul and Dakin, Helen and Buckell, John and Woon, Yuan-Liang and Roope, Laurence and Chandran, Arunah and Mustapha, Feisul I. and Gregg, Edward W. and Clarke, Philip M. (2023) Trends in all-cause mortality among adults with diagnosed type 2 diabetes in West Malaysia: 2010-2019. Diabetes Research and Clinical Practice, 205. ISSN 0168-8227, DOI https://doi.org/10.1016/j.diabres.2023.110944.
Full text not available from this repository.Abstract
Aims: We determined 10-year all-cause mortality trends in diagnosed type 2 diabetes (T2D) population in West Malaysia, a middle-income country in the Western-Pacific region.Methods: One million T2D people aged 40-79 registered in the National Diabetes Registry (2009-2018) were linked to death records (censored on 31 December 2019). Standardized absolute mortality rates and standardized mortality ratios (SMRs) were estimated relative to the Malaysian general population, and standardized to the 2019 registry population with respect to sex, age group, and disease duration.Results: Overall all-cause standardized mortality rates were unchanged in both sexes. Rates increased in males aged 40-49 (annual average percent change AAPC]: 2.46 % 95 % CI 0.42 %, 4.55 %]) and 50-59 (AAPC: 1.91 % 95 % CI 0.73 %, 3.10 %]), and females aged 40-49 (AAPC: 3.39 % 95 % CI 1.32 %, 5.50 %]). In both sexes, rates increased among those with 1) > 15 years disease duration, 2) prior cardiovascular disease, and 3) Bumiputera (Malay/native) ethnicity. The overall SMR was 1.83 (95 % CI 1.80, 1.86) for males and 1.85 (95 % CI 1.82, 1.89) for females, being higher in younger age groups and showed an increasing trend in those with either > 15 years disease duration or prior cardiovascular disease.Conclusions: Mortality trends worsened in certain T2D population in Malaysia.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Cardiovascular disease; Diabetes mellitus; Epidemiology; Ethnicity; Health disparity; Middle-income country |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine > Medicine Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 08 Sep 2025 06:08 |
| Last Modified: | 08 Sep 2025 06:08 |
| URI: | http://eprints.um.edu.my/id/eprint/50614 |
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