Esfahan, Zahra Maghareh and Izhar, Shamsul and Izadiyan, Zahra and Toozandehjani, Meysam and Yoshida, Huroyuki (2023) One-step synthesis of bovine serum albumin nanoparticles by hydrothermal green treatment. Iranian Journal of Chemistry & Chemical Engineering-International English Edition, 42 (6). pp. 1731-1743. ISSN 1021-9986,
Full text not available from this repository.Abstract
The non-toxic BSA-based NanoParticles (NPs) are developed without any additives with hydrothermal SubCritical Water Treatment (SCWT). The optimum BSA-based NPs are gained by applying Response Surface Methodology (RSM) based on particle size, zeta potential, and polydispersity. The SCWT conditions are optimized in terms of these three dependent variables, which have significant impacts on the BSA-based NPs application. The optimum BSA-based NPs prepared with 2.73% (w/v) of initial BSA solution concentration, the lowest initial concentration that is used to synthesize BSA-based NPs by now. The SCWT condition of 173 degrees C and 2.07 min of SCWT holding time shows that the zeta potential of -38.87 mV with the finest particle size and PI (147.32 nm and 0.24, respectively) is the optimized composition. The fabricated BSA-based NPs are characterized by the UV-vis, screening electron microscope (SEM), and stability assessment study.
| Item Type: | Article |
|---|---|
| Funders: | None |
| Uncontrolled Keywords: | Bovine serum albumin; Nanoparticle; hydrothermal; optimization; subcritical water treatment; green recovery; blood waste; drug delivery; response surface methodology |
| Subjects: | Q Science > QD Chemistry T Technology > TP Chemical technology |
| Divisions: | Faculty of Engineering > Department of Chemical Engineering |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 08 Nov 2025 04:03 |
| Last Modified: | 08 Nov 2025 04:03 |
| URI: | http://eprints.um.edu.my/id/eprint/49767 |
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