Current advances of nanocellulose application in biomedical field

Leong, M. Y. and Kong, Y. L. and Harun, M. Y. and Looi, C. Y. and Wong, Won Fen (2023) Current advances of nanocellulose application in biomedical field. Carbohydrate Research, 532. ISSN 0008-6215, DOI https://doi.org/10.1016/j.carres.2023.108899.

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Abstract

Nanocellulose (NC) is a natural fiber that can be extracted in fibrils or crystals form from different natural sources, including plants, bacteria, and algae. In recent years, nanocellulose has emerged as a sustainable biomaterial for various medicinal applications including drug delivery systems, wound healing, tissue engineering, and antimicrobial treatment due to its biocompatibility, low cytotoxicity, and exceptional water holding capacity for cell immobilization. Many antimicrobial products can be produced due to the chemical functionality of nanocellulose, such disposable antibacterial smart masks for healthcare use. This article discusses comprehensively three types of nanocellulose: cellulose nanocrystals (CNC), cellulose nanofibrils (CNF), and bacterial nanocellulose (BNC) in view of their structural and functional properties, extraction methods, and the distinctive biomedical applications based on the recently published work. On top of that, the biosafety profile and the future perspectives of nanocellulose-based biomaterials have been further discussed in this review.

Item Type: Article
Funders: Ministry of Higher Education, Malaysia [Grant no. FRGS/1/2021/SKK06/TAYLOR/02/2]
Uncontrolled Keywords: Nanocellulose; Drug delivery system; Tissue engineering; Antimicrobial
Subjects: R Medicine
Divisions: Faculty of Medicine > Medical Microbiology Department
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 30 Oct 2025 07:24
Last Modified: 30 Oct 2025 07:24
URI: http://eprints.um.edu.my/id/eprint/48693

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