Sun, Dan-Qin and Targher, Giovanni and Byrne, Christopher D. and Wheeler, David C. and Wong, Vincent Wai-Sun and Fan, Jian-Gao and Tilg, Herbert and Yuan, Wei-Jie and Wanner, Christoph and Gao, Xin and Long, Michelle T. and Kanbay, Mehmet and Nguyen, Mindie H. and Navaneethan, Sankar D. and Yilmaz, Yusuf and Huang, Yuli and Gani, Rino A. and Marzuillo, Pierluigi and Boursier, Jerome and Zhang, Huijie and Jung, Chan-Young and Chai, Jin and Valenti, Luca and Papatheodoridis, George and Musso, Giovanni and Wong, Yu-Jun and El-Kassas, Mohamed and Mendez-Sanchez, Nahum and Sookoian, Silvia and Pavlides, Michael and Duseja, Ajay and Holleboom, Adriaan G. and Shi, Junping and Chan, Wah-Kheong and Fouad, Yasser and Yang, Junwei and Treeprasertsuk, Sombat and Cortez-Pinto, Helena and Hamaguchi, Masahide and Romero-Gomez, Manuel and Al Mahtab, Mamun and Ocama, Ponsiano and Nakajima, Atsushi and Dai, Chunsun and Eslam, Mohammed and Wei, Lai and George, Jacob and Zheng, Ming-Hua (2023) An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease. Hepatobiliary Surgery and Nutrition, 12 (3). 386+. ISSN 2304-3881, DOI https://doi.org/10.21037/hbsn-22-421.
Full text not available from this repository.Abstract
Background: With the rising global prevalence of fatty liver disease related to metabolic dysfunction, the association of this common liver condition with chronic kidney disease (CKD) has become increasingly evident. In 2020, the more inclusive term metabolic dysfunction-associated fatty liver disease (MAFLD) was proposed to replace the term non-alcoholic fatty liver disease (NAFLD). The observed association between MAFLD and CKD and our understanding that CKD can be a consequence of underlying metabolic dysfunction support the notion that individuals with MAFLD are at higher risk of having and developing CKD compared with those without MAFLD. However, to date, there is no appropriate guidance on CKD in individuals with MAFLD. Furthermore, there has been little attention paid to the link between MAFLD and CKD in the Nephrology community. Methods and Results: Using a Delphi-based approach, a multidisciplinary panel of 50 international experts from 26 countries reached a consensus on some of the open research questions regarding the link between MAFLD and CKD. Conclusions: This Delphi-based consensus statement provided guidance on the epidemiology, mechanisms, management and treatment of MAFLD and CKD, as well as the relationship between the severity of MAFLD and risk of CKD, which establish a framework for the early prevention and management of these two common and interconnected diseases.
| Item Type: | Article |
|---|---|
| Funders: | None |
| Uncontrolled Keywords: | Metabolic dysfunction-associated fatty liver disease (MAFLD); non-alcoholic fatty liver disease (NAFLD); chronic kidney disease (CKD); consensus |
| Subjects: | R Medicine > RD Surgery |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 27 Oct 2025 04:30 |
| Last Modified: | 27 Oct 2025 04:30 |
| URI: | http://eprints.um.edu.my/id/eprint/48381 |
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