Djinbachian, Roupen and Rex, Douglas K. and Chiu, Han-Mo and Fukami, Norio and Aihara, Hiroyuki and Bastiaansen, Barbara A. J. and Bechara, Robert and Bhandari, Pradeep and Bhatt, Amit and Bourke, Michael J. and Byeon, Jeong-Sik and Cardoso, Daniela and Chino, Akiko and Chiu, Philip W. Y. and Dekker, Evelien and Draganov, Peter V. and Elkholy, Shaimaa and Emura, Fabian and Goldblum, John and Haji, Amyn and Ho, Shiaw-Hooi and Jung, Yunho and Kawachi, Hiroshi and Khashab, Mouen and Khomvilai, Supakij and Kim, Eun Ran and Maselli, Roberta and Messmann, Helmut and Moons, Leon and Mori, Yuichi and Nakanishi, Yukihiro and Ngamruengphong, Saowanee and Parra-Blanco, Adolfo and Pellise, Maria and Pinto, Rafael Castilho and Pioche, Mathieu and Pohl, Heiko and Rastogi, Amit and Repici, Alessandro and Sethi, Amrita and Singh, Rajvinder and Suzuki, Noriko and Tanaka, Shinji and Vieth, Michael and Yamamoto, Hironori and Yang, Dong-Hoon and Yokoi, Chizu and Saito, Yutaka and von Renteln, Daniel (2024) International consensus on the management of large (≥20 mm) colorectal laterally spreading tumors: World Endoscopy Organization Delphi study. Digestive Endoscopy, 36 (11). pp. 1253-1268. ISSN 0915-5635, DOI https://doi.org/10.1111/den.14826.
Full text not available from this repository.Abstract
ObjectivesThere have been significant advances in the management of large (>= 20 mm) laterally spreading tumors (LSTs) or nonpedunculated colorectal polyps; however, there is a lack of clear consensus on the management of these lesions with significant geographic variability especially between Eastern and Western paradigms. We aimed to provide an international consensus to better guide management and attempt to homogenize practices.MethodsTwo experts in interventional endoscopy spearheaded an evidence-based Delphi study on behalf of the World Endoscopy Organization Colorectal Cancer Screening Committee. A steering committee comprising six members devised 51 statements, and 43 experts from 18 countries on six continents participated in a three-round voting process. The Grading of Recommendations, Assessment, Development and Evaluations tool was used to assess evidence quality and recommendation strength. Consensus was defined as >= 80% agreement (strongly agree or agree) on a 5-point Likert scale.ResultsForty-two statements reached consensus after three rounds of voting. Recommendations included: three statements on training and competency; 10 statements on preresection evaluation, including optical diagnosis, classification, and staging of LSTs; 14 statements on endoscopic resection indications and technique, including statements on en bloc and piecemeal resection decision-making; seven statements on postresection evaluation; and eight statements on postresection care.ConclusionsAn international expert consensus based on the current available evidence has been developed to guide the evaluation, resection, and follow-up of LSTs. This may provide guiding principles for the global management of these lesions and standardize current practices.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Endoscopy, Endoscopic mucosal resection; Endoscopic resection; Endoscopic submucosal dissection; Gastrointestinal cancer; Neoplasia |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RD Surgery |
| Divisions: | Faculty of Medicine > Medicine Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 20 Jan 2025 08:47 |
| Last Modified: | 20 Jan 2025 08:47 |
| URI: | http://eprints.um.edu.my/id/eprint/47578 |
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