COMBINED KNEE OSTEOARTHRITIS AND DIABETES IS ASSOCIATED WITH REDUCED MUSCLE STRENGTH, PHYSICAL INACTIVITY, AND POORER QUALITY OF LIFE

Seow, Shi Rui and Mat, Sumaiyah and Teoh, Jun Jie and Yusup, Amyra Mohamad and Rajab, Nor Fadilah and Ismail, Intan Safinar and Singh, Devinder Kaur Ajit and Shahar, Suzana and Tan, Maw Pin and Berenbaum, Francis (2024) COMBINED KNEE OSTEOARTHRITIS AND DIABETES IS ASSOCIATED WITH REDUCED MUSCLE STRENGTH, PHYSICAL INACTIVITY, AND POORER QUALITY OF LIFE. Journal of Rehabilitation Medicine, 56. jrm39986. ISSN 1650-1977, DOI https://doi.org/10.2340/jrm.v56.39986.

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Official URL: https://doi.org/10.2340/jrm.v56.39986

Abstract

Objective: This study delves into the intriguing connection between knee osteoarthritis and diabetes in Malaysia. Specifically, the exacerbation of knee osteoarthritis in the presence of diabetes in terms of symptoms, physical performance, physical activity, psychological status, social participation, and quality of life was discussed. Design: This cross-sectional study recruited adults aged 50 and above by convenient sampling and grouped them into: knee osteoarthritis-diabetes-, knee osteoarthritis+diabetes-, knee osteoarthritisdiabetes+, and knee osteoarthritis+diabetes+. Subjects/Patients: Of 436 recruited participants, 261 (59.8%) participants reported knee osteoarthritis. Methods: Handgrip strength, Timed Up and Go test, 6 Meter Walk Test, and 5 Times Sit to Stand Test were measured using standardized procedures. Six questionnaires were administered for the remaining parameters. Results: Across groups, there were significant differences: 6 Meter Walk Test (p p = 0.024), Timed Up and Go test (p p = 0.020), and 5 Times Sit to Stand Test (p p < 0.001), quality of life (p p = 0.009), and physical activity (p p = 0.036). Knee osteoarthritis+diabetes+ was independently associated with reduced hand- grip strength, 5 Times Sit to Stand Test, quality of life, and physical inactivity after adjustment. Knee osteoarthritis+diabetes- was independently associated with reduced Timed Up and Go test and social isolation. Conclusion: The findings revealed the diabetic knee osteoarthritis subgroup's unique physical and psychosocial features of reduced muscle strength and physical inactivity. Future studies should investigate whether managing metabolic factors, and enhancing physical activity and strength exercises, can reduce knee osteoarthritis symptoms and disease severity.

Item Type: Article
Funders: Fundamental Research Grant Scheme, Ministry of Higher Education, Malaysia (FRGS/1/2021/SKK0/UKM/02/15), Research University Grant, Universiti Kebangsaan Malaysia (GUP-2021-058)
Uncontrolled Keywords: diabetes mellitus; exercise; mental health; osteo- arthritis; knee; physical functional performance; quality of life; social isolation
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine > Medicine Department
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 22 Nov 2024 07:04
Last Modified: 22 Nov 2024 07:04
URI: http://eprints.um.edu.my/id/eprint/47113

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