Biopolymer based nanoparticles and their therapeutic potential in wound healing - A review

Kumar, Mohit and Mahmood, Syed and Chopra, Shruti and Bhatia, Amit (2024) Biopolymer based nanoparticles and their therapeutic potential in wound healing - A review. International Journal of Biological Macromolecules, 267 (2). p. 131335. ISSN 0141-8130, DOI https://doi.org/10.1016/j.ijbiomac.2024.131335.

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Official URL: https://doi.org/10.1016/j.ijbiomac.2024.131335

Abstract

Nanoparticles (NPs) have been extensively investigated for their potential in nanomedicine. There is a significant level of enthusiasm about the potential of NPs to bring out a transformative impact on modern healthcare. NPs can serve as effective wound dressings or delivery vehicles due to their antibacterial and pro-wound-healing properties. Biopolymer-based NPs can be manufactured using various food-grade biopolymers, such as proteins, polysaccharides, and synthetic polymers, each offering distinct properties suitable for different applications which include collagen, polycaprolactone, chitosan, alginate, and polylactic acid, etc. Their biodegradable and biocompatible nature renders them ideal nanomaterials for applications in wound healing. Additionally, the nanofibers containing biopolymer-based NPs have shown excellent anti-bacterial and wound healing activity like silver NPs. These NPs represent a paradigm shift in wound healing therapies, offering targeted and personalized solutions for enhanced tissue regeneration and accelerated wound closure. The current review focuses on biopolymer NPs with their applications in wound healing.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Nanoparticles; Wound healing; Biopolymers; Antibacterial activity
Subjects: R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Pharmacy
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 09 Jan 2025 03:14
Last Modified: 09 Jan 2025 03:14
URI: http://eprints.um.edu.my/id/eprint/46981

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