Cavanagh, Erika and Crawford, Kylie and Hong, Jesrine Gek Shan and Fontanarosa, Davide and Edwards, Christopher and Wille, Marie-Luise and Hong, Jennifer and Clifton, Vicki L. and Kumar, Sailesh (2024) The Relationship between Placental Shear Wave Elastography and Fetal Weight-A Prospective Study. Journal of Clinical Medicine, 13 (15). p. 4432. ISSN 2077-0383, DOI https://doi.org/10.3390/jcm13154432.
Full text not available from this repository.Abstract
Background/Objectives: The utility of shear wave elastography (SWE) as an adjunct to ultrasound biometry and Doppler velocimetry for the examination of placental dysfunction and suboptimal fetal growth is unclear. To date, limited data exist correlating the mechanical properties of placentae with fetal growth. This study aimed to investigate the relationship between placental shear wave velocity (SWV) and ultrasound estimated fetal weight (EFW), and to ascertain if placental SWV is a suitable proxy measure of placental function in the surveillance of small-for-gestational-age (SGA) pregnancies. Methods: This prospective, observational cohort study compared the difference in placental SWV between SGA and appropriate-for-gestational-age (AGA) pregnancies. There were 221 women with singleton pregnancies in the study cohort-136 (61.5%) AGA and 85 (38.5%) SGA. Fetal biometry, Doppler velocimetry, the deepest vertical pocket of amniotic fluid, and mean SWV were measured at 2-4-weekly intervals from recruitment to birth. Results: There was no difference in mean placental SWV in SGA pregnancies compared to AGA pregnancies, nor was there any relationship to EFW. Conclusions: Although other studies have shown some correlation between increased placental stiffness and SGA pregnancies, our investigation did not support this. The mechanical properties of placental tissue in SGA pregnancies do not result in placental SWVs that are apparently different from those of AGA controls. As this study did not differentiate between constitutionally or pathologically small fetuses, further studies in growth-restricted cohorts would be of benefit.
| Item Type: | Article |
|---|---|
| Funders: | National Health & Medical Research Council (NHMRC) of Australia, Mater Foundation, University of Queensland scholarship |
| Uncontrolled Keywords: | shear wave elastography; shear wave velocity; placental function; placental stiffness; fetal growth; fetal growth restriction; small for gestational age; ultrasound |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine > Obstetrics & Gynaecology Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 09 Apr 2025 03:25 |
| Last Modified: | 09 Apr 2025 03:25 |
| URI: | http://eprints.um.edu.my/id/eprint/46723 |
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