A review of the epidemiology of invasive fungal infections in Asian patients with hematological malignancies (2011-2021)

Iyadorai, Thevambiga and Tay, Sun Tee and Liong, Chee Chiat and Samudi, Chandramathi and Chow, Lai Chee and Cheong, Chin Sum and Velayuthan, Rukumani Devi and Tan, Sen Mui and Gan, Gin Gin (2024) A review of the epidemiology of invasive fungal infections in Asian patients with hematological malignancies (2011-2021). Epidemiologic Reviews, 46 (1). pp. 1-12. ISSN 0193-936X, DOI https://doi.org/10.1093/epirev/mxae003.

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Abstract

The incidence of invasive fungal infection (IFI) is increasing, especially among patients diagnosed with hematological malignancies due to their immunocompromised nature. Other risk factors include advanced age, exposure to immunosuppressants, neutropenia, and catheter use. Some of the most common IFI organisms reported are Candida and Aspergillus species, and other fungal species, including Scedosporium, Trichosporon, Cryptococcus, and Fusarium have also increasingly been reported in the past years. However, the epidemiologic data on IFI among patients with hematological malignancies in Asian countries are lacking. Therefore, we investigated published epidemiologic data on such cases from the past 10 years (2011-2021) and discuss the challenges faced in the diagnosis and management of IFIs in Asia.

Item Type: Article
Funders: Pfizer Malaysia [Grant no. PV067–2019], Universiti Malaya [Grant no. RK001–2020]
Uncontrolled Keywords: Invasive fungal infection; Hematological malignancies; Treatment; Challenges; Asian
Subjects: R Medicine
Divisions: Faculty of Medicine > Medical Microbiology Department
Faculty of Medicine > Medicine Department
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 22 Oct 2025 03:32
Last Modified: 22 Oct 2025 03:32
URI: http://eprints.um.edu.my/id/eprint/46476

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