George, Reuben and Chow, Li Sze and Lim, Kheng Seang and Tan, Li Kuo and Ramli, Norlisah (2022) Correlation between multimodal radiographic features and preoperative seizure in brain tumor using machine learning. In: 2022 IEEE-EMBS Conference on Biomedical Engineering and Sciences, LECBES, 07-09 December 2022, Kuala Lumpur.
Full text not available from this repository.Abstract
Tumor-related epilepsy (TRE) refers to the condition in which primary brain tumors cause recurring seizures. A model that classifies brain tumors as epileptogenic or non-epileptogenic could improve prognosis and treatment methods for TRE. This study aims to identify which MRI sequences and machine learning algorithms (MLAs) could be used to build the most accurate epileptogenic tumor classification model. T1W, T2W, T2W FLAIR and T1W contrast-enhanced scans were acquired from 24 glioma patients, 8 with and 16 without pre- operative epilepsy. A total of 88 features were extracted from the MRI sequences, including tumor location, volume, and several first order textural features derived from gray level cooccurrence matrices (GLCM). Each feature was then used as a predicting variable for 9 MLAs (7 variants of support vector machines (SVMs) and 2 variants of logistic regression) to construct classification models. The top 11 classification models had testing accuracies above or equal to 75%. These models all used SVM variants instead of logistic regression variants. The classification model that used tumor location, and the one that used tumor volume, had testing accuracies of 100% and 87.5% respectively. The 9 other top classification models used GLCM features extracted from the contrast T1W sequence.
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Funders: | Impact-Oriented Interdisciplinary Research Grant (IIRG) [Grant No: IIRG003-2020HWB] |
| Uncontrolled Keywords: | Outcomes; Gliomas; Regions |
| Subjects: | Q Science > QA Mathematics > QA75 Electronic computers. Computer science R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms Koh Ai Peng |
| Date Deposited: | 16 Jul 2024 03:09 |
| Last Modified: | 16 Jul 2024 06:58 |
| URI: | http://eprints.um.edu.my/id/eprint/46293 |
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