Vaccine for diabetes-where do we stand?

Chellappan, Dinesh Kumar and Bhandare, Richie R. and Shaik, Afzal B. and Prasad, Krishna and Suhaimi, Nurfatihah Azlyna Ahmad and Yap, Wei Sheng and Das, Arpita and Banerjee, Pradipta and Ghosh, Nandini and Guith, Tanner and Das, Amitava and Balakrishnan, Sarannya and Candasamy, Mayuren and Mayuren, Jayashree and Palaniveloo, Kishneth and Gupta, Gaurav and Singh, Sachin Kumar and Dua, Kamal (2022) Vaccine for diabetes-where do we stand? International Journal of Molecular Sciences, 23 (16). ISSN 1661-6596, DOI https://doi.org/10.3390/ijms23169470.

Full text not available from this repository.

Abstract

Diabetes is an endocrinological disorder with a rapidly increasing number of patients globally. Over the last few years, the alarming status of diabetes has become a pivotal factor pertaining to morbidity and mortality among the youth as well as middle-aged people. Current developments in our understanding related to autoimmune responses leading to diabetes have developed a cause for concern in the prospective usage of immunomodulatory agents to prevent diabetes. The mechanism of action of vaccines varies greatly, such as removing autoreactive T cells and inhibiting the interactions between immune cells. Currently, most developed diabetes vaccines have been tested in animal models, while only a few human trials have been completed with positive outcomes. In this review, we investigate the undergoing clinical trial studies for the development of a prototype diabetes vaccine.

Item Type:	Article
Funders:	Deanship of Graduate Studies and Research, Ajman University
Uncontrolled Keywords:	diabetes; vaccines; clinical trials; insulin; GLP
Subjects:	R Medicine > R Medicine (General)
Divisions:	Deputy Vice Chancellor (Research & Innovation) Office > Institute of Ocean and Earth Sciences
Depositing User:	Ms Koh Ai Peng
Date Deposited:	23 Jul 2024 04:16
Last Modified:	23 Jul 2024 04:16
URI:	http://eprints.um.edu.my/id/eprint/46268

Actions (login required)

View Item