Ahmad, Wan Azman Wan and Ghapar, Abdul Kahar Abdul and Abidin, Hafisyatul Aiza Zainal and Karthikesan, Dharmaraj and Ross, Noel Thomas and Kader, Muhamad Ali S. K. Abdul and Loch, Alexander and Mahendran, Kauthaman and Ramli, Ahmad Wazi and Ong, Tiong Kiam and Amin, Nor Hanim Mohd and Lee, Chuey Yan and Hassan, Hamat Hamdi Che and Abidin, Siti Khairani Zainal and Liew, Houng Bang and Ho, Wing Sze and Ghazi, Azmee Mohd (2024) Characteristics of patients admitted with heart failure: Insights from the first Malaysian Heart Failure Registry. ESC Heart Failure, 11 (2). pp. 727-736. ISSN 2055-5822, DOI https://doi.org/10.1002/ehf2.14608.
Full text not available from this repository.Abstract
AimsHeart failure (HF) is a growing health problem, yet there are limited data on patients with HF in Malaysia. The Malaysian Heart Failure (MY-HF) Registry aims to gain insights into the epidemiology, aetiology, management, and outcome of Malaysian patients with HF and identify areas for improvement within the national HF services.Methods and resultsThe MY-HF Registry is a 3-year prospective, observational study comprising 2717 Malaysian patients admitted for acute HF. We report the description of baseline data at admission and outcomes of index hospitalization of these patients. The mean age was 60.2 +/- 13.6 years, 66.8% were male, and 34.3% had de novo HF. Collectively, 55.7% of patients presented with New York Heart Association (NYHA) Class III or IV; ischaemic heart disease was the most frequent aetiology (63.2%). Most admissions (87.3%) occurred via the emergency department, with 13.7% of patients requiring intensive care, and of these, 21.8% needed intubation. The proportion of patients receiving guideline-directed medical therapy increased at discharge (84.2% vs. 93.6%). The median length of stay (LOS) was 5 days, and in-hospital mortality was 2.9%. Predictors of LOS and/or in-hospital mortality were age, NYHA class, estimated glomerular filtration rate, and comorbid anaemia. LOS and in-hospital mortality were similar regardless of ejection fraction.ConclusionsThe MY-HF Registry showed that the HF population in Malaysia is younger, predominantly male, and ischaemic-driven and has good prospects with hospitalization for optimization of treatment. These findings suggest a need to reassess current clinical practice and guide resource allocation to improve patient outcomes.
| Item Type: | Article |
|---|---|
| Funders: | Novartis Corporation (Malaysia) Sdn Bhd, Novartis medical team |
| Uncontrolled Keywords: | Acute decompensated heart failure; Baseline demographics; Guideline-directed medical therapy utilization; In-hospital outcome |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Universiti Malaya Medical Centre (UMMC) |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 14 Nov 2024 05:35 |
| Last Modified: | 14 Nov 2024 05:35 |
| URI: | http://eprints.um.edu.my/id/eprint/45933 |
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