Bioactivity and remineralization potential of modified glass ionomer cement: A systematic review of the impact of calcium and phosphate ion release

Tuygunov, Nozimjon and Khairunnisa, Zahra and Yahya, Noor Azlin and Aziz, Azwatee Abdul and Zakaria, Myrna Nurlatifah and Israilova, Nigora Amanullaevna and Cahyanto, Arief (2024) Bioactivity and remineralization potential of modified glass ionomer cement: A systematic review of the impact of calcium and phosphate ion release. Dental Materials Journal, 43 (1). pp. 1-10. ISSN 0287-4547, DOI https://doi.org/10.4012/dmj.2023-132.

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Official URL: https://doi.org/10.4012/dmj.2023-132

Abstract

This systematic review investigates the effectiveness of calcium and phosphate ions release on the bioactivity and remineralization potential of glass ionomer cement (GIC). Electronic databases, including PubMed-MEDLINE, Scopus, and Web of Science, were systematically searched according to PRISMA guidelines. This review was registered in the PROSPERO database. Five eligible studies on modifying GIC with calcium and phosphate ions were included. The risk of bias was assessed using the RoBDEMAT tool. The incorporation of these ions into GIC enhanced its bioactivity and remineralization properties. It promoted hydroxyapatite formation, which is crucial for remineralization, increased pH and inhibited cariogenic bacteria growth. This finding has implications for the development of more effective dental materials. This can contribute to improved oral health outcomes and the management of dental caries, addressing a prevalent and costly oral health issue. Nevertheless, comprehensive longitudinal investigations are needed to evaluate the clinical efficacy of this GIC's modification.

Item Type: Article
Funders: Universiti Malaya
Uncontrolled Keywords: Glass ionomer cement; Calcium; Phosphate; Bioactive; Remineralization
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Dentistry
Faculty of Dentistry > Department of Restorative Dentistry
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 08 Nov 2024 08:52
Last Modified: 08 Nov 2024 08:52
URI: http://eprints.um.edu.my/id/eprint/45706

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