Gopalan, Thirumaaran and Muhamad, Mohd Ridha and Hoe, Victor Chee Wai and Hassandarvish, Pouya (2024) N95 respirator hybrid decontamination method using Ultraviolet Germicidal Irradiation (UVGI) coupled with Microwave-Generated Steam (MGS). PLoS ONE, 19 (2). e0296871. ISSN 1932-6203, DOI https://doi.org/10.1371/journal.pone.0296871.
Full text not available from this repository.Abstract
The Coronavirus Disease 2019 (COVID-19) pandemic has induced a critical supply of personal protective equipment (PPE) especially N95 respirators. Utilizing respirator decontamination procedures to reduce the pathogen load of a contaminated N95 respirator can be a viable solution for reuse purposes. In this study, the efficiency of a novel hybrid respirator decontamination method of ultraviolet germicidal irradiation (UVGI) which utilizes ultraviolet-C (UV-C) rays coupled with microwave-generated steam (MGS) against feline coronavirus (FCoV) was evaluated. The contaminated 3M 1860 respirator pieces were treated with three treatments (UVGI-only, MGS-only, and Hybrid-UVGI + MGS) with variable time. The virucidal activity was evaluated using the TCID50 method. The comparison of decontamination efficiency of the treatments indicated that the hybrid method achieved at least a pathogen log reduction of 4 logs, faster than MGS and UVGI. These data recommend that the proposed hybrid decontamination system is more effective comparatively in achieving pathogen log reduction of 4 logs.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Malaya COVID-19 Related Special Research Grant (UMCSRG - CSRG003-2020ST) |
| Uncontrolled Keywords: | N95 respirator; hybrid decontamination; Ultraviolet Germicidal Irradiation; Microwave-Generated Steam |
| Subjects: | R Medicine > R Medicine (General) T Technology > TJ Mechanical engineering and machinery |
| Divisions: | Faculty of Engineering Faculty of Engineering > Department of Mechanical Engineering Faculty of Medicine > Social & Preventive Medicine Deputy Vice Chancellor (Research & Innovation) Office > Tropical Infectious Diseases Research and Education Centre |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 07 Nov 2024 04:04 |
| Last Modified: | 07 Nov 2024 04:04 |
| URI: | http://eprints.um.edu.my/id/eprint/45657 |
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