Amil, Muhammad Amirul and Rahman, Syarifah Nur Syed Abdul and Yap, Lee Fah and Razak, Fathilah Abdul and Bakri, Marina Mohd and Salem, Lamis S. O. and Lim, Xiu Yi and Reduan, Nur Athirah and Sim, Kae Shin (2024) Antimicrobial and Antiproliferative Effects of Zingiberaceae Oils: A Natural Solution for Oral Health. Chemistry & Biodiversity, 21 (3). ISSN 1612-1872, DOI https://doi.org/10.1002/cbdv.202301836.
Full text not available from this repository.Abstract
Essential oils have been recognised for their potential benefits in oral care. The aim of this study was to evaluate the antibacterial and antiproliferative activity of essential oils derived from four Zingiberaceae species. A combination of GC/MS and GC-FID was employed to analyse these essential oils. The results showed that beta-myrcene (79.77 %) followed by ethyl-cinnamate (40.14 %), beta-curcumene (34.90 %), and alloaromadendrene (25.15 %) as the primary constituents of Curcuma mangga, Curcuma xanthorrhiza, Kaempferia galanga and Curcuma aeruginosa, respectively. The Zingiberaceae oils were tested for their antibacterial activity against oral bacteria using the disc diffusion test. Curcuma xanthorrhiza oil showed the largest inhibition zones against Streptococcus mitis (19.50 +/- 2.22 mm) and Streptococcus sanguinis (15.04 +/- 3.05 mm). Similarly, Curcuma mangga oil exhibited significant antibacterial activity against Streptococcus mutans (12.55 +/- 0.45 mm) and mixed oral bacteria (15.03 +/- 3.82 mm). Furthermore, the MTT viability assay revealed moderate inhibitory activity of these essential oils against H103 and ORL-204 oral cancer cells. The study findings demonstrate that Curcuma xanthorrhiza and Curcuma mangga essential oils have potent antibacterial properties, suggesting their potential use as natural alternatives to synthetic antibacterial agents in oral care products. However, further investigations are necessary to fully explore their therapeutic applications. image
| Item Type: | Article |
|---|---|
| Funders: | Ministry of Education for the Fundamental Research (FRGS/1/2020/SKK0/UM/02/39), Ministry of Education for the Fundamental Research Grant Scheme (FRGS), Cancer Research Malaysia |
| Uncontrolled Keywords: | Antiproliferative; essential oil; oral bacteria; oral health; Zingiberaceae |
| Subjects: | Q Science > QH Natural history R Medicine > RK Dentistry |
| Divisions: | Faculty of Dentistry > Department of Oral & Craniofacial Sciences Faculty of Science > Institute of Biological Sciences |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 04 Nov 2024 08:46 |
| Last Modified: | 04 Nov 2024 08:46 |
| URI: | http://eprints.um.edu.my/id/eprint/45587 |
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