Teow, Jun Yao and Zhang, Qinyi and Abidin, Syafiq Asnawi Zainal and Tan, Chuey Chuan and Karsani, Saiful Anuar and Othman, Iekhsan and Chen, Yeng and Lakshmipriya, Thangavel and Gopinath, Subash C.B. (2024) Pioneering biosensor approaches for oral squamous cell carcinoma diagnosis: A comprehensive review. Process Biochemistry, 141. pp. 71-81. ISSN 1359-5113, DOI https://doi.org/10.1016/j.procbio.2024.02.015.
Full text not available from this repository.Abstract
Oral squamous cell carcinoma (OSCC) remains a significant global challenge in the medical field, accounting for approximately 300,000 incidences and 145,000 mortalities annually. Studies suggest that early cancer detection is the most vital factor in improving OSCC patient outcomes. Effective clinical diagnosis methods for early OSCC are needed urgently. OSCC biomarkers are identified to be associated with cancer progression and biosensors are devices developed to detect the presence of OSCC biomarkers to allow early cancer diagnosis. Biosensor technology has significant potential in providing rapid and accurate detection of OSCC biomarkers with high sensitivity and specificity. Biosensors have various advantages compared to conventional diagnostic methods such as being non-invasive, low-cost, and convenient. Biosensors hold the potential to be adopted as point-ofcare-testing (POCT) devices by bringing biosensor technology to the patients. This review aims to provide a comprehensive review by describing and comparing different categories of OSCC biosensors based on their advantages and drawbacks. The recent obstacles and opportunities for developing effective biosensors for cancer diagnosis are summarized.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Malaya Impact-Oriented Interdisciplinary Research Grant Programme (IIRG) (IIRG002A-2021FNW) |
| Uncontrolled Keywords: | Biomarker; Oral carcinoma; Post -translational modifications; Nanomaterial |
| Subjects: | Q Science > QH Natural history R Medicine > R Medicine (General) R Medicine > RK Dentistry |
| Divisions: | Faculty of Dentistry Faculty of Medicine Faculty of Science > Institute of Biological Sciences |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 26 Sep 2024 02:13 |
| Last Modified: | 26 Sep 2024 02:13 |
| URI: | http://eprints.um.edu.my/id/eprint/45204 |
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