Mohamed, W.A.S. and Ishak, K.N. and Baharum, N. and Zainudin, N.A.Z. and Lim, Han Yin and Noh, M.F.M. and Ahmad, Wan Azman Wan and Huri, Hasniza Zaman and Zuhdi, A.S.M. and Sukahri, S. and Govindaraju, K. and Abd Jamil, A.H. (2024) Ethnic disparities and its association between epicardial adipose tissue thickness and cardiometabolic parameters. Adipocyte, 13 (1). p. 2314032. ISSN 2162-3945, DOI https://doi.org/10.1080/21623945.2024.2314032.
Full text not available from this repository.Abstract
Excessive deposit of epicardial adipose tissue (EAT) were recently shown to be positively correlated with cardiovascular disease (CVD). This study aims to investigate the thickness of EAT and its association with the components of metabolic syndrome among multi-ethnic Malaysians with and without acute coronary syndrome (ACS). A total of 213 patients were recruited, with the thickness of EAT were quantified non-invasively using standard two-dimensional echocardiography. EAT thickness among the Malaysian population was prompted by several demographic factors and medical comorbidities, particularly T2DM and dyslipidaemia. ACS patients have significantly thicker EAT compared to those without ACS (4.1 mm vs 3.7 mm, p = 0.035). Interestingly, among all the races, Chinese had the thickest EAT distribution (4.6 mm vs 3.8 mm), with age (p = 0.04 vs p < 0.001), and overall diastolic blood pressure (p = 0.028) was also found to be associated with EAT thickness. Further study is warranted to investigate its role as a cardiovascular risk marker among Malaysians with ACS.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Epicardial adipose tissue; acute coronary syndrome; echocardiography; multi-ethnic Malaysia; metabolic syndrome |
| Subjects: | R Medicine R Medicine > RS Pharmacy and materia medica |
| Divisions: | Faculty of Medicine Faculty of Pharmacy |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 13 Sep 2024 05:01 |
| Last Modified: | 13 Sep 2024 05:01 |
| URI: | http://eprints.um.edu.my/id/eprint/45084 |
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