Bah, Mohd Nizam Mat and Zahari, Norazah and Boparam, Baljit Kaur and Sapian, Mohd Hanafi (2024) The incidence and factors associated with the recurrence of supraventricular tachycardia in children: 15 years experience from middle-income country. Pediatric Cardiology, 45 (2). 292 – 299. ISSN 0172-0643, DOI https://doi.org/10.1007/s00246-023-03374-9.
Full text not available from this repository.Abstract
Limited data are available concerning supraventricular tachycardia (SVT) recurrence. Hence, this study aimed to determine the incidence, outcome, and factors associated with SVT recurrence. This retrospective, observational, population-based study was conducted among children with SVT from 2006 to 2020. The primary outcome measure was SVT recurrence. Kaplan Meier analysis was used to estimate SVT-free at 1, 5, and 10 years after diagnosis. Cox regression analysis was used to identify independent factors associated with recurrence. There were 156 patients with SVT with a median age at diagnosis of 1.9 years (Interquartile range IQR 11 days to 8.7 years) and follow-up for a median of 3.5 years (IQR 1.7 to 6.1 years). 35 patients (22%) had recurrent SVT at a median age of 7.8 years (IQR 4.4 to 12 years). Infants with Wolff-Parkinson-White Syndrome (WPW) had the highest recurrence (11/16, 68%), with 33% SVT-free at 5 years follow-up. The lowest recurrence rate was observed in neonatal diagnosis (2/54, 3.7%) with 98% SVT-free at 5 years follow-up. The independent factors associated with the recurrence of SVT were the diagnosis of WPW with an adjusted hazard ratio (aHR) of 5.2 (95% CI 2.4–11.2), age of more than 1 year at diagnosis (aHR 3.7 95% CI 1.4–9.7), and combine with or need second-line therapy (aHR 4.0 95% CI 1.5–10.7). One in five children with SVT experienced a recurrence, which is more likely for those with WPW, multiple maintenance therapy, and older age at first presentation. Whereas neonates with non-WPW may benefit from shorter maintenance therapy. © 2024, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
| Item Type: | Article |
|---|---|
| Funders: | Health Malaysia |
| Uncontrolled Keywords: | Recurrence; Risk factors; Supraventricular tachycardia; Wolff-Parkinson-White Syndrome |
| Subjects: | R Medicine > RJ Pediatrics |
| Divisions: | Faculty of Medicine > Paediatrics Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 01 Jul 2024 04:33 |
| Last Modified: | 01 Jul 2024 04:33 |
| URI: | http://eprints.um.edu.my/id/eprint/44832 |
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