N95 respirator hybrid decontamination method using Ultraviolet Germicidal Irradiation (UVGI) coupled with Microwave-Generated Steam (MGS)

Gopalan, Thirumaaran and Muhamad, Mohd Ridha and Hoe, Victor Chee Wai and Hassandarvish, Pouya (2024) N95 respirator hybrid decontamination method using Ultraviolet Germicidal Irradiation (UVGI) coupled with Microwave-Generated Steam (MGS). PLoS ONE, 19 (2 Febr). ISSN 1932-6203, DOI https://doi.org/10.1371/journal.pone.0296871.

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Abstract

The Coronavirus Disease 2019 (COVID-19) pandemic has induced a critical supply of personal protective equipment (PPE) especially N95 respirators. Utilizing respirator decontamination procedures to reduce the pathogen load of a contaminated N95 respirator can be a viable solution for reuse purposes. In this study, the efficiency of a novel hybrid respirator decontamination method of ultraviolet germicidal irradiation (UVGI) which utilizes ultraviolet-C (UV-C) rays coupled with microwave-generated steam (MGS) against feline coronavirus (FCoV) was evaluated. The contaminated 3M 1860 respirator pieces were treated with three treatments (UVGI-only, MGS-only, and Hybrid—UVGI + MGS) with variable time. The virucidal activity was evaluated using the TCID50 method. The comparison of decontamination efficiency of the treatments indicated that the hybrid method achieved at least a pathogen log reduction of 4 logs, faster than MGS and UVGI. These data recommend that the proposed hybrid decontamination system is more effective comparatively in achieving pathogen log reduction of 4 logs. Copyright: © 2024 Gopalan et al.

Item Type: Article
Funders: Universiti Malaya [Grant no. UMCSRG - CSRG003-2020ST]
Uncontrolled Keywords: Decontamination; Equipment reuse; Microwaves; N95 Respirators; Pandemics; Steam; Ultraviolet rays
Subjects: R Medicine > R Medicine (General)
T Technology > TJ Mechanical engineering and machinery
Divisions: Faculty of Engineering > Department of Mechanical Engineering
Faculty of Medicine > Social & Preventive Medicine
Deputy Vice Chancellor (Research & Innovation) Office > Tropical Infectious Diseases Research and Education Centre
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 02 Jul 2024 03:44
Last Modified: 02 Jul 2024 03:44
URI: http://eprints.um.edu.my/id/eprint/44826

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