Zelenev, Alexei and Michael, Laura and Li, Jianghong and Altice, Frederick L. (2024) Social networks, secondary syringe exchange, and opioid agonist therapy retention among people who inject drugs in Hartford, CT. International Journal Of Drug Policy, 123. ISSN 0955-3959, DOI https://doi.org/10.1016/j.drugpo.2023.104250.
Full text not available from this repository.Abstract
Background: Opioid agonist therapies (OAT) and harm reduction such as syringe service programs (SSP) have been shown to be effective in preventing adverse outcomes such as overdose deaths, HIV and Hepatitis C in-fections among people who inject drugs (PWID). The importance of social network influence on disease trans-mission is well established, yet the interplay between harm reduction and network structures is, generally, not well understood. This study aims to analyze how social networks can mediate the harm reduction effects asso-ciated with secondary exchange through syringe service programs (SSP) and opioid agonist therapies (OAT) among injection network members.Methods: Sociometric data on networks on people who inject drugs from Hartford, CT, which were collected in 2012-2013, provided assessment of risk behaviors among 1574 injection network members, including partici-pation in OAT and SSP. Subject's network characteristics were examined in relation to retention in OAT, as well as secondary syringe exchange using exponential random graph model (ERGM) and regression.Results: Based on the analysis, we found that probability of individuals being retained in OAT was positively associated with the OAT retention status of their peers within the network. Using simulations, we found that higher levels of positive correlation of OAT retention among network members can result in reduced risk of transmission of HIV to network partners on OAT. In addition, we found that secondary syringe exchange engagement was associated with higher probability of sharing of paraphernalia and unsterile needles at the network level.Conclusions: Understanding how networks mediate risk behaviors is crucial for making progress toward ending the HIV epidemic.
| Item Type: | Article |
|---|---|
| Funders: | United States Department of Health & Human Services National Institutes of Health (NIH) - USA NIH National Institute on Drug Abuse (NIDA), National Institute for Health Career Development award [K01 DA037826], National Institute for Health Career Development award [K24 DA017072], United States Department of Health & Human Services National Institutes of Health (NIH) - USA NIH National Institute on Drug Abuse (NIDA) [R01 DA0315940] |
| Uncontrolled Keywords: | Harm reduction; Secondary syringe exchange; Opioid agonist therapy; People who inject drugs; Networks; ERGMs |
| Subjects: | H Social Sciences > HN Social history and conditions. Social problems. Social reform R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RC Internal medicine |
| Divisions: | Faculty of Medicine Centre of Excellence for Research in AIDS (CERiA) |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 27 Jun 2024 05:00 |
| Last Modified: | 27 Jun 2024 05:00 |
| URI: | http://eprints.um.edu.my/id/eprint/44246 |
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