Rajandram, Retnagowri and Koong, Jun Kit and Quek, Kia F. and Lee, Eng G. and Abdul Razack, Azad Hassan and Kuppusamy, Shanggar (2022) Ethnic differences in serum testosterone concentration among Malay, Chinese and Indian men: A cross-sectional study. Clinical Endocrinology, 97 (3). pp. 303-309. ISSN 0300-0664, DOI https://doi.org/10.1111/cen.14682.
Full text not available from this repository.Abstract
Objective To investigate non-urological patients with multiple comorbidities for factors contributing towards differences in testosterone concentration in multiethnic Malaysian men. Design An observational study. Patients Sexually active men, >= 40 years, with no known urological problems, were recruited at the phlebotomy clinic at our centre. Measurements A brief history along with latest fasting lipid profile and plasma glucose levels were obtained. An Aging Male Symptoms questionnaire was administered; waist circumference (WC) and serum testosterone concentration were measured. Statstical Analysis Analysis of testosterone concentration between Malay, Indian and Chinese men was performed. Statistical tests such as analysis of variance, chi(2) test, univariate and multivariable regression were performed. Any p < .05 was noted as statistically significant. Results Among the 604 participants analysed, mean testosterone concentration was significantly lower in Malays (15.1 +/- 5.9 nmol/L) compared to the Chinese (17.0 +/- 5.9 nmol/L) and Indian (16.1 +/- 6.5 nmol/L) participants. The mean WC was also found to be higher among the Malays (96.1 +/- 10.9 cm) compared to Chinese (92.6 +/- 9.6 cm) and Indians (95.6 +/- 9.9 cm). Testosterone concentration tended to be lower with higher age, but this was not statistically significant (p > .05). In the multivariable analysis only Malay ethnicity, WC >= 90 cm and low high-density lipoprotein (HDL) were associated with lower testosterone concentration. Conclusion In this study, Malaysian men of Malay origin had lower testosterone concentration compared with Indian and Chinese men. WC and low HDL were also associated with lower testosterone concentrations.
| Item Type: | Article |
|---|---|
| Funders: | UM Wellness Fund |
| Uncontrolled Keywords: | Androgens; Central obesity; Men's health; Metabolic syndrome; Race |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine > Surgery Department Universiti Malaya Medical Centre (UMMC) |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 25 Oct 2023 06:20 |
| Last Modified: | 25 Oct 2023 06:20 |
| URI: | http://eprints.um.edu.my/id/eprint/41758 |
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