Cheng, Jian Yuan and Samudram, Hemalatha and Lee, Christina Lai Ling and Nadarajan, Veera Sekaran (2022) Deviations in red cell blood component temperature during laboratory processing and at blood return monitored by a time-temperature indicator device. Transfusion Medicine, 32 (6). pp. 484-491. ISSN 0958-7578, DOI https://doi.org/10.1111/tme.12924.
Full text not available from this repository.Abstract
Objectives To evaluate the performance and utility of a time-temperature indicator (TTI) to determine the cumulative exposure time (CET) of red cell components (RCC) to temperatures above 10 degrees C occurring within and outside the transfusion laboratory. Background and Objectives Blood centres often use the `30 or 60-min rule' for accepting RCC exposed to room temperature (RT) back into inventory. Effective monitoring of these temperature deviations is however lacking. Materials and Methods A Timestrip PLUS (R) TP153 10 degrees C (TS + 10) TTI was attached to RCC units after preparation of the unit in the blood bank or on issue to the ward, to track the CET > 10 degrees C during laboratory processing and outside the transfusion laboratory. Results The mean CET of 153 RCC tracked within the laboratory was 56 min. Sixty-four (41.8%) and 34 (22.2%) of RCC had core temperature (CT) >10 degrees C for more than 30 and 60 min, respectively. Among the 69 RCC that were returned unused, 27 (39.1%), 17 (24.6%) and 5 (7.2%) RCC units had CT >10 degrees C for more than 30, 60 and 120 min respectively. Conclusion A large proportion of RCC have CT >10 degrees C exceeding 30 min during handling within the transfusion laboratory, as well as when RCC are returned unused from transfusion locations. Corrective measures should be implemented to better manage the cold chain to avoid undesirable consequences to blood transfusion. A temperature sensitive device that can also indicate CET can be employed to objectively monitor the period that RCC remained at a CT that exceeds 10 degrees C.
| Item Type: | Article |
|---|---|
| Funders: | None |
| Uncontrolled Keywords: | 30-min rule; Blood component; Quality; Red blood cells; Time-temperature indicator |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Universiti Malaya Medical Centre (UMMC) |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 22 Nov 2023 06:32 |
| Last Modified: | 22 Nov 2023 06:32 |
| URI: | http://eprints.um.edu.my/id/eprint/40387 |
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