High referral accuracy for oral cancers and oral potentially malignant disorders using telemedicine

Haron, Nabihah and Rajendran, Senthilmani and Kallarakkal, Thomas George and Zain, Rosnah B and Ramanathan, Anand and Abraham, Mannil Thomas and Lau, Shin Hin and Cheng, Lai Choo and Chong, Sherrie Mei Yee and Mohamed Azahar, Farah Aliya and Mohamad Zaini, Zuraiza and Chan, Siew Wui and Goh, Yet Ching and Lim, Daniel and Khairi, Juliana and Abidin, Marzuki Zainal and Abdul Rahman, Zainal Ariff and Liew, Chee Sun and Fong, Siew Chinn and Yang, Yi-Hsin and Ismail, Siti Mazlipah and Cheong, Sok Ching (2023) High referral accuracy for oral cancers and oral potentially malignant disorders using telemedicine. Oral Diseases, 29 (2). pp. 380-389. ISSN 1354-523X, DOI https://doi.org/10.1111/odi.13892.

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Abstract

Objective To evaluate the accuracy of MeMoSA (R), a mobile phone application to review images of oral lesions in identifying oral cancers and oral potentially malignant disorders requiring referral. Subjects and Methods A prospective study of 355 participants, including 280 with oral lesions/variants was conducted. Adults aged >= 18 treated at tertiary referral centres were included. Images of the oral cavity were taken using MeMoSA (R). The identification of the presence of lesion/variant and referral decision made using MeMoSA (R) were compared to clinical oral examination, using kappa statistics for intra-rater agreement. Sensitivity, specificity, concordance and F1 score were computed. Images were reviewed by an off-site specialist and inter-rater agreement was evaluated. Images from sequential clinical visits were compared to evaluate observable changes in the lesions. Results Kappa values comparing MeMoSA (R) with clinical oral examination in detecting a lesion and referral decision was 0.604 and 0.892, respectively. Sensitivity and specificity for referral decision were 94.0% and 95.5%. Concordance and F1 score were 94.9% and 93.3%, respectively. Inter-rater agreement for a referral decision was 0.825. Progression or regression of lesions were systematically documented using MeMoSA (R). Conclusion Referral decisions made through MeMoSA (R) is highly comparable to clinical examination demonstrating it is a reliable telemedicine tool to facilitate the identification of high-risk lesions for early management.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Clinical oral examination; Early detection; Oral cancer; Oral medicine; Oral potentially malignant disorders; Telemedicine
Subjects: R Medicine > R Medicine (General)
R Medicine > RK Dentistry
R Medicine > RK Dentistry > Oral surgery
Divisions: Faculty of Dentistry
Faculty of Dentistry > Department of Oral & Maxillofacial Clinical Sciences
Depositing User: Ms Zaharah Ramly
Date Deposited: 09 Nov 2024 07:35
Last Modified: 09 Nov 2024 07:35
URI: http://eprints.um.edu.my/id/eprint/39635

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