Mansor, Azura and Ariffin, Ainnur Farhana and Yusof, Norimah and Mohd, Suhaili and Ramalingam, Saravana and Saad, Amir Putra Md and Baharin, Ruzalina and Min, Ng Wuey (2023) Effects of processing and gamma radiation on mechanical properties and organic composition of frozen, freeze-dried and demineralised human cortical bone allograft. Cell and Tissue Banking, 24 (1). pp. 25-35. ISSN 1389-9333, DOI https://doi.org/10.1007/s10561-022-10013-9.
Full text not available from this repository.Abstract
Bone processing and radiation were reported to influence mechanical properties of cortical bones due in part to structural changes and denaturation of collagen composition. This comparative study was to determine effects of bone processing on mechanical properties and organic composition, and to what extent the radiation damaging after each processing. Human femur cortical bones were processed by freezing, freeze-drying and demineralisation and then gamma irradiated at 5, 15, 20, 25 and 50 kGy. In the compression test, freeze drying significantly decreased the Young's Modulus by 15%, while demineralisation reduced further by 90% (P < 0.05) when compared to the freezing. Only demineralisation significantly reduced ultimate strength of bone by 93% (P < 0.05). In the bending test, both freeze drying and demineralisation significantly reduced the ultimate strength and the work to failure. Radiation at 25 kGy showed no effect on compression for ultimate strength in each processing group. However, high dose of 50 k
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Bending test; Bone processing; Compression test; FTIR; Gamma radiation; Human cortical bone |
| Subjects: | R Medicine R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Faculty of Law Faculty of Medicine > Orthopaedic Surgery Department |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 05 Nov 2024 01:29 |
| Last Modified: | 05 Nov 2024 01:29 |
| URI: | http://eprints.um.edu.my/id/eprint/39546 |
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