Herliana, Heri and Yusuf, Harmas Yazid and Laviana, Avi and Wandawa, Ganesha and Cahyanto, Arief (2023) Characterization and analysis of chitosan-gelatin composite-based biomaterial effectivity as local hemostatic agent: A systematic review. Polymers, 15 (3). ISSN 2073-4360, DOI https://doi.org/10.3390/polym15030575.
Full text not available from this repository.Abstract
Chitosan and gelatin were the most widely used natural materials in pharmaceutical and medical fields, especially as local hemostatic agents, independently or as a composite material with the addition of other active substances. Chitosan and gelatin have excellent properties in biocompatibility, biodegradability, non-toxicity and water absorption capacity. The objective of this review was to analyze the characteristics of chitosan-gelatin (CG) composite-based biomaterial and its effectivity as a local hemostatic agent. We used PRISMA guidelines and the PICO framework to compile this review. The findings demonstrated that the CG composite-based biomaterial had excellent physical, chemical, mechanical properties and local hemostatic agent activity by adding other active substances such as oxidized fibers (OF), silica nanoparticles (SiNPs), calcium (Ca) and biphasic calcium phosphate (BCP) or by setting the CG composite proportion ratio.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Chitosan-gelatin; Composite material; Hemostatic agent |
| Subjects: | R Medicine > RK Dentistry |
| Divisions: | Faculty of Dentistry |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 06 Jul 2023 03:15 |
| Last Modified: | 06 Jul 2023 03:15 |
| URI: | http://eprints.um.edu.my/id/eprint/38698 |
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