Wong, Won Fen and Ang, Kuan Ping and Sethi, Gautam and Looi, Chung Yeng (2023) Recent advancement of medical patch for transdermal drug delivery. Medicina-Lithuania, 59 (4). ISSN 1010-660X, DOI https://doi.org/10.3390/medicina59040778.
Full text not available from this repository.Abstract
Transdermal patches are a non-invasive method of drug administration. It is an adhesive patch designed to deliver a specific dose of medication through the skin and into the bloodstream throughout the body. Transdermal drug delivery has several advantages over other routes of administration, for instance, it is less invasive, patient-friendly, and has the ability to bypass first-pass metabolism and the destructive acidic environment of the stomach that occurs upon the oral ingestion of drugs. For decades, transdermal patches have attracted attention and were used to deliver drugs such as nicotine, fentanyl, nitroglycerin, and clonidine to treat various diseases or conditions. Recently, this method is also being explored as a means of delivering biologics in various applications. Here, we review the existing literatures on the design and usage of medical patches in transdermal drug delivery, with a focus on the recent advances in innovation and technology that led to the emergence of smart, dissolvable/biodegradable, and high-loading/release, as well as 3D-printed patches.
| Item Type: | Article |
|---|---|
| Funders: | Ministry of Education - Singapore, Ministry of Higher Education, Malaysia, FRGS/1/2020/SKK0/TAYLOR/02/6, Universiti Malaya, GPF004B-2020 |
| Uncontrolled Keywords: | Transdermal; Drug delivery; Medical patch; Development and technology |
| Subjects: | R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 27 Nov 2023 06:00 |
| Last Modified: | 27 Nov 2023 06:00 |
| URI: | http://eprints.um.edu.my/id/eprint/38381 |
Actions (login required)
 |
View Item |
