Recent development of nanomaterials for transdermal drug delivery

Leong, Moong Yan and Kong, Yeo Lee and Burgess, Kevin and Wong, Won Fen and Sethi, Gautam and Looi, Chung Yeng (2023) Recent development of nanomaterials for transdermal drug delivery. Biomedicines, 11 (4). ISSN 2227-9059, DOI https://doi.org/10.3390/biomedicines11041124.

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Abstract

Nano-engineered medical products first appeared in the last decade. The current research in this area focuses on developing safe drugs with minimal adverse effects associated with the pharmacologically active cargo. Transdermal drug delivery, an alternative to oral administration, offers patient convenience, avoids first-pass hepatic metabolism, provides local targeting, and reduces effective drug toxicities. Nanomaterials provide alternatives to conventional transdermal drug delivery including patches, gels, sprays, and lotions, but it is crucial to understand the transport mechanisms involved. This article reviews the recent research trends in transdermal drug delivery and emphasizes the mechanisms and nano-formulations currently in vogue.

Item Type: Article
Funders: Malaysian Ministry of Higher Education (MOHE) [Grant No: FRGS/1/2021/SKK06/TAYLOR/02/2], Universiti Malaya [Grant No: GPF004A-2020]
Uncontrolled Keywords: Nanomaterials; Transdermal drug delivery; Transdermal mechanisms
Subjects: R Medicine > R Medicine (General) > Medical technology
Divisions: Faculty of Medicine > Medical Microbiology Department
Depositing User: Ms Zaharah Ramly
Date Deposited: 10 Nov 2024 03:04
Last Modified: 10 Nov 2024 03:04
URI: http://eprints.um.edu.my/id/eprint/38346

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