Viera, Adam and Bromberg, Daniel J. and Whittaker, Shannon and Refsland, Bryan M. and Stanojlovic, Milena and Nyhan, Kate and Altice, Frederick L. (2020) Adherence to and retention in medications for opioid use disorder among adolescents and young adults. Epidemiologic Reviews, 42 (1). pp. 41-56. ISSN 0193-936X, DOI https://doi.org/10.1093/epirev/mxaa001.
Full text not available from this repository.Abstract
The volatile opioid epidemic is associated with higher levels of opioid use disorder (OUD) and negative health outcomes in adolescents and young adults. Medications for opioid use disorder (MOUD) demonstrate the best evidence for treating OUD. Adherence to and retention in MOUD, defined as continuous engagement in treatment, among adolescents and young adults, however, is incompletely understood. We examined the state of the literature regarding the association of age with adherence to and retention in MOUD using methadone, buprenorphine, or naltrexone among persons aged 10-24 years, along with related facilitators and barriers. All studies of MOUD were searched for that examined adherence, retention, or related concepts as an outcome variable and included adolescents or young adults. Search criteria generated 10,229 records; after removing duplicates and screening titles and abstracts, 587 studies were identified for full-text review. Ultimately, 52 articles met inclusion criteria for abstraction and 17 were selected for qualitative coding and analysis. Younger age was consistently associated with shorter retention, although the overall quality of included studies was low. Several factors at the individual, interpersonal, and institutional levels, such as concurrent substance use, MOUD adherence, family conflict, and MOUD dosage and flexibility, appeared to have roles in MOUD retention among adolescents and young adults. Ways MOUD providers can tailor treatment to increase retention of adolescents and young adults are highlighted, as is the need for more research explaining MOUD adherence and retention disparities in this age group.
| Item Type: | Article |
|---|---|
| Funders: | United States Department of Health & Human Services National Institutes of Health (NIH) - USA NIH National Institute of Mental Health (NIMH) (T32MH20031), United States Department of Health & Human Services National Institutes of Health (NIH) - USA NIH National Institute on Drug Abuse (NIDA) (R01 DA033679), United States Department of Health & Human Services National Institutes of Health (NIH) - USA NIH National Institute on Drug Abuse (NIDA) (K24 DA017072) |
| Uncontrolled Keywords: | Adolescents; Buprenorphine; Medications for opioid use disorder; Methadone; Naltrexone; Opioid use disorder; Retention; Young adults |
| Subjects: | R Medicine > RA Public aspects of medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 16 Jan 2023 07:11 |
| Last Modified: | 16 Jan 2023 07:11 |
| URI: | http://eprints.um.edu.my/id/eprint/38119 |
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