An overview of rickettsiae in Southeast Asia: Vector-animal-human interface

Low, Van Lun and Tan, Tiong Kai and Khoo, Jing Jing and Lim, Fang Shiang and AbuBakar, Sazaly (2020) An overview of rickettsiae in Southeast Asia: Vector-animal-human interface. Acta Tropica, 202. ISSN 0001-706X, DOI https://doi.org/10.1016/j.actatropica.2019.105282.

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Abstract

Rickettsioses are emerging, and re-emerging diseases caused by obligate intracellular arthropod-borne bacteria that infect humans and animals worldwide. Various rickettsiae such as Orientia, Rickettsia, Anaplasma and Ehrlichia have been circulated in companion, domesticated and wild animals through bites of infected ticks, fleas, lice or mites. This review summarizes the infections of rickettsiae, including the newly discovered regional species Rickettsia thailandii, Candidatus Rickettsia sepangensis, Candidatus Rickettsia johorensis, Candidatus Rickettsia laoensis, Candidatus Rickettsia mahosotii, Candidatus Rickettsia khammouanensis, Candidatus Anaplasma pangolinii, and other novel genotypes in vectors, humans and animals in Southeast Asia. Issues on some unidentified rickettsiae that elicit immune responses and production of antibodies that are cross-reactive with the antigens used are discussed. Knowledge gaps which required attention are also identified in this review.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Infectious diseases; Tropical; Vector-borne; Zoonosis; Rickettsia; Anaplasmataceae; Scrub typhus; Spotted fever; Typhus fever
Subjects: R Medicine
R Medicine > RA Public aspects of medicine
R Medicine > RM Therapeutics. Pharmacology
Divisions: Faculty of Medicine
Faculty of Medicine > Parasitology Deparment
Deputy Vice Chancellor (Research & Innovation) Office > Tropical Infectious Diseases Research and Education Centre
Depositing User: Ms Zaharah Ramly
Date Deposited: 25 Oct 2024 04:37
Last Modified: 25 Oct 2024 04:37
URI: http://eprints.um.edu.my/id/eprint/36926

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