Andiappan, Kavitha and Shahrizaila, Nortina and Abdul Latif, Lydia (2020) Disability profile and the factors affecting functional outcome in Malaysian motor neurone disease population. Neurology Asia, 25 (3). pp. 305-312. ISSN 1823-6138,
Full text not available from this repository.Abstract
Background & Objective: The accurate knowledge on the individual spectrum of disabilities and the course of the disease is important for timely medical and rehabilitation management of patients with motor neurone disease in terms of clinical prediction and clinical decision making. The objectives of this study are to identify the disability profile, functional outcome, fatigue and the correlation between fatigue and domains of functional decline in Malaysian motor neurone disease population. Methods: Thirty motor neurone disease patients undergoing rehabilitation programme in University Malaya Medical Centre completed a questionnaire to report the symptoms and problems affecting their daily life. Revised Amyotrophic Lateral Sclerosis Functional Rating Scale depicting their function level and Fatigue Severity Scale to determine their fatigability status. Revised Amyotrophic Lateral Sclerosis Functional Rating Scale was repeated after 6 months to measure the functional decline. Results: The mean age was 60 years with men more affected than women (3:1). The main symptoms reported were weakness (93%) and weight loss (83%). Majority of them had difficulties in performing domestic chores (77%) and engaging in social life (73%). No statistically significant factors were found to be associated with functional decline among the Malaysian motor neurone disease patients. Decline in respiratory function was shown to be statistically significant among the fatigued motor neurone disease patients (p=0.032). Conclusion: This study is a stepping stone to future researches pertaining to rehabilitation in motor neuron disease which helps to tackle this population's multifaceted disabilities ensuring a meaningful quality of life. A paradigm shift is needed to provide pulmonary rehabilitation to these population especially the ones with fatigue to dampen the progressive deterioration of respiratory function enhancing their quality of life.
| Item Type: | Article |
|---|---|
| Funders: | None |
| Uncontrolled Keywords: | Disability profile; Motor neurone disease; Functional outcome; Rehabilitation; Fatigability |
| Subjects: | R Medicine > RC Internal medicine |
| Divisions: | Faculty of Medicine > Medicine Department |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 27 Nov 2023 02:23 |
| Last Modified: | 03 Dec 2023 01:29 |
| URI: | http://eprints.um.edu.my/id/eprint/36417 |
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