Takeshita, Akihiro and Watanabe, Hiroko and Yamada, Chiaki and Nadarajan, Veera Sekaran and Permpikul, Parichart and Sinkitjasub, Attapong and Natalie, Chan Pui Ha and Zhao, Shuming and Han, Kyou Sup and Kim, Dae Won and Suh, Jang Soo and Kim, Hyun Ok and Kawabata, Kinuyo and Ishimaru, Ken and Ohtomo, Naoki and Yamada, Naotomo and Tomoda, Yutaka and Yurugi, Kimiko and Ohto, Hitoshi (2020) Erythrocyte Alloimmunity and Genetic Variance: Results from the Collaborative Study of Alloimmunity to Antigen Diversity in Asian Populations (All ADP). TRANSFUSION AND APHERESIS SCIENCE, 59 (5). ISSN 14730502, DOI https://doi.org/10.1016/j.transci.2020.102944.
Full text not available from this repository.Abstract
As an East-Asian international study, we evaluated erythrocyte alloimmunity by gender and history of transfusion or pregnancy. In total, data from more than 1,826,000 patients were analyzed, from whom 26,170 irregular erythrocyte antibodies were detected in 22,653 cases. Antibody frequencies in these cases were as follows: anti-E, 26.8%; anti-Lea, 20.0%; anti-P1, 7.1%; anti-M, 6.4%; anti-Mia, 5.6%; anti-c + E, 5.6%; anti-Leb, 4.6%; anti-D, 2.8%; anti-Fyb, 2.6%; anti-Lea+Leb, 2.5%; anti-Dia, 2.0%; and others. For pregnant patients, anti-D (12.7%) was statistically more frequent. For transfused patients, anti-E (37.3%), anti-c + E (9.5%), anti-C + e (3.3%) and anti-Jka (3.1%) were significantly more frequent.
| Item Type: | Article |
|---|---|
| Funders: | Ministry of Education, Culture, Sports, Science and Technology (Grant No. 16K08933, 19K07935) |
| Uncontrolled Keywords: | Alloimmunity; Erythrocyte; Asian people; Japanese; Patients; Gender; Pregnancy; Transfusion; Antibody |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 28 Dec 2023 13:38 |
| Last Modified: | 28 Dec 2023 13:38 |
| URI: | http://eprints.um.edu.my/id/eprint/36383 |
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