Khosropanah, Pegah and Ho, Eric Tatt-Wei and Lim, Kheng Seang and Fong, Si Lei and Le, Minh-An Thuy and Narayanan, Vairavan (2020) EEG Source Imaging (ESI) utility in clinical practice. Biomedical Engineering / Biomedizinische Technik, 65 (6). pp. 673-682. ISSN 0013-5585, DOI https://doi.org/10.1515/bmt-2019-0128.
Full text not available from this repository.Abstract
Epilepsy surgery is an important treatment modality for medically refractory focal epilepsy. The outcome of surgery usually depends on the localization accuracy of the epileptogenic zone (EZ) during pre-surgical evaluation. Good localization can be achieved with various electrophysiological and neuroimaging approaches. However, each approach has its own merits and limitations. Electroencephalography (EEG) Source Imaging (ESI) is an emergingmodel-based computational technique to localize cortical sources of electrical activity within the brain volume, three-dimensionally. ESI based pre-surgical evaluation gives an overall clinical yield of 73-91%, depending on choice of head model, inverse solution and EEG electrode density. It is a cost effective, non-invasive method which provides valuable additional information in presurgical evaluation due to its high localizing value specifically inMRI-negative cases, extra or basal temporal lobe epilepsy, multifocal lesions such as tuberous sclerosis or cases with multiple hypotheses. Unfortunately, less than 1% of surgical centers in developing countries use this method as a part of pre-surgical evaluation. This review promotes ESI as a useful clinical tool especially for patients with lesion-negative MRI to determine EZ cost-effectively with high accuracy under the optimized conditions.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Malaya [Grant No: RP052C-17HTM] |
| Uncontrolled Keywords: | EEG source imaging; Epilepsy; Epilepsy surgery; Epileptogenic zone |
| Subjects: | R Medicine R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RD Surgery |
| Divisions: | Faculty of Medicine Faculty of Medicine > Medicine Department |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 29 Nov 2023 05:48 |
| Last Modified: | 29 Nov 2023 05:48 |
| URI: | http://eprints.um.edu.my/id/eprint/36220 |
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