Fadzli, Farhana and Rahmat, Kartini and Ramli, Marlina Tanty and Rozalli, Faizatul Izza and Hooi, Teoh Kean and Fadzli, Ahmad Nazran and Hoong, See Mee and Mohd Ramli, Norlisah and Mohd Taib, Nur Aishah (2021) Spectrum of imaging findings of papillary breast disease: A radiopathological review in a tertiary center. Medicine, 100 (16). ISSN 0025-7974, DOI https://doi.org/10.1097/MD.0000000000025297.
Full text not available from this repository.Abstract
To evaluate the clinical and imaging findings of papillary breast neoplasm and review the pathologic correlation at a tertiary center. Retrospective study of patients diagnosed with benign and malignant papillary lesions between 2008 to 2018. 147 patients were identified with histology diagnosis of papillary lesions. The clinical, imaging, and pathological characteristics were reviewed. Patient cohort included 147 women diagnosed with papillary lesions (mean age at diagnosis 53.8 years) and were divided into 3 histology groups (benign, atypical, and malignant). Common clinical presentations were breast lump (n = 60) and nipple discharge (n = 29), 48 patients were asymptomatic. Only 37 were detected as a mass lesion on mammogram. The presence of mass lesion on mammogram was the most common feature in all 3 papillary lesion groups, and with the presence of asymmetric density, were the 2 mammographic features significantly associated (P < .05) with malignancy. All lesions were detected on ultrasound. The most common sonographic features for all 3 groups were the presence of a mass and irregular shape. Among all the sonographic features assessed, larger size, presence of vascularity and absence of dilated ducts were significantly associated (P < .05) with malignancy. Feature pattern recognition of the variety of benign, atypical and malignant papillary neoplasm on ultrasound and mammogram, with emphasis on size, presence of vascularity and dilated ducts on ultrasound and presence of mass, and architectural distortion on mammogram, is important in the assessment of patients with suspected ductal lesions to facilitate optimal treatment and surgical care.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Malaya (RP052B-17HTM), Universiti Malaya (FP0-172019A), Universiti Malaya (BK052-2017), Universiti Malaya (FRGS/1/2019/SKK03/UM/01/1) |
| Uncontrolled Keywords: | Breast neoplasms; Mammography; Papilloma; Ultrasonography |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RC Internal medicine |
| Divisions: | Faculty of Medicine > Biomedical Imaging Department |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 02 Sep 2022 08:22 |
| Last Modified: | 02 Sep 2022 08:22 |
| URI: | http://eprints.um.edu.my/id/eprint/34179 |
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