Sa'at, Hamizah and Lee, Yew-Kong and Yoon, Sook-Yee and Wong, Siu Wan and Woo, Yin Ling and Barlow-Stewart, Kristine and Mohd Taib, Nur Aishah (2022) The needs of Southeast Asian BRCA mutation carriers considering risk-reducing salpingo-oophorectomy: A qualitative study. Familial Cancer, 21 (1). pp. 21-33. ISSN 1389-9600, DOI https://doi.org/10.1007/s10689-021-00232-6.
Full text not available from this repository.Abstract
The decision to have risk-reducing salpingo-oophorectomy (RRSO) by BRCA mutation carriers to reduce the risk of ovarian cancer is difficult. The choice involves trade-offs in terms of its risks and benefits. To date, understanding the decision-making needs of RRSO among Southeast Asian BRCA mutation carriers is limited. This study aimed to explore the decision-making needs of Malaysian BRCA mutation carriers as an exemplar for the Southeast Asian community. In-depth interviews and clinic observations were conducted with 31 BRCA mutation carriers and analysed thematically. The core theme identified was `Coping with complex information and alleviating uncertainties' with the following subthemes: (1) the need for an adjustment period, (2) information support, (3) social support and, (4) religious support. We found that women required time to accept their BRCA mutation status before they were ready to make a risk-reducing choice; that understanding complex genetic information and multiple risk management options can be an overwhelming experience; and obtaining further information and a second opinion were challenging. Many described the need for experiential information from other peer-carriers who had undergone RRSO. Support from their spouse and family members was thought to be essential for them to feel reassured with their decision. Many relied on religion to positively cope with cancer risk and cancer worry; Muslim BRCA carriers sought religious guidance through prayers and Islamic fatwas to feel more certain about their RRSO decision. These findings underscore the importance of the provision of resources and support that includes input from peers, husband, family members and religion to underpin the decision-making needs of Malaysian BRCA mutation carriers considering RRSO.
| Item Type: | Article |
|---|---|
| Funders: | Terry Fox Run-Cancer Research Malaysia Research Grant, University Malaya [PG075-2016A] |
| Uncontrolled Keywords: | BRCA mutation carriers; Risk-reducing salpingo-oophorectomy; Medical decision-making; Southeast Asia |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RD Surgery |
| Divisions: | Faculty of Medicine > Obstetrics & Gynaecology Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 25 Apr 2022 02:22 |
| Last Modified: | 25 Apr 2022 02:22 |
| URI: | http://eprints.um.edu.my/id/eprint/33841 |
Actions (login required)
 |
View Item |
