Lee, Zheng-Yii and Hasan, Mohd Shahnaz and Day, Andrew G. and Ng, Ching Choe and Ong, Su Ping and Yap, Cindy Sing Ling and Engkasan, Julia Patrick and Barakatun-Nisak, Mohd Yusof and Heyland, Daren K. (2022) Initial development and validation of a novel nutrition risk, sarcopenia, and frailty assessment tool in mechanically ventilated critically ill patients: The NUTRIC-SF score. Journal of Parenteral And Enteral Nutrition, 46 (3). pp. 499-507. ISSN 0148-6071, DOI https://doi.org/10.1002/jpen.2194.
Full text not available from this repository.Abstract
Background Nutrition risk, sarcopenia, and frailty are interrelated. They may be due to suboptimal or prevented by optimal nutrition intake. The combination of nutrition risk (modified nutrition risk in the critically ill mNUTRIC]), sarcopenia (SARC-F combined with calf circumference SARC-CALF]), and frailty (clinical frailty scale CFS]) in a single score may better predict adverse outcomes and prioritize resources for optimal nutrition in the intensive care unit (ICU) Methods This is a retrospective analysis of a single-center prospective observational study that enrolled mechanically ventilated adults with expected >= 96 h of ICU stay. SARC-F and CFS questionnaires were administered to patient's next-of-kin and mNUTRIC were calculated. Right calf circumference was measured. Nutrition data were collected from nursing record. The high-risk scores (mNUTRIC >= 5, SARC-CALF > 10, or CFS >= 4) of these variables were combined to become the nutrition risk, sarcopenia, and frailty (NUTRIC-SF) score (range: 0-3). Results Eighty-eight patients were analyzed. Increasing mNUTRIC was independently associated with 60-day mortality, whereas increasing SARC-CALF and CFS showed a strong trend towards a higher 60-day mortality. Discriminative ability of NUTRIC-SF for 60-day mortality is better than its component (C-statistics, 0.722; 95% confidence interval CI], 0.677-0.868). Every increment of 300 kcal/day and 30 g/day is associated with a trend towards higher rate of discharge alive for high (>= 2; adjusted hazard ratio, 1.453 95% CI, 0.991-2.130] for energy; 1.503 0.936-2.413] for protein) but not low (<2) NUTRIC-SF score. Conclusion NUTRIC-SF may be a clinically relevant risk stratification tool in the ICU.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Critical care; Frailty; Nutrition risk; Sarcopenia |
| Subjects: | Q Science > QP Physiology R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | Faculty of Medicine > Anaesthesiology Department Faculty of Medicine > Rehabilitation Medicine Department |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 25 Apr 2022 08:05 |
| Last Modified: | 25 Apr 2022 08:05 |
| URI: | http://eprints.um.edu.my/id/eprint/33816 |
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