Contextual and individual factors associated with knowledge, awareness and attitude on liver diseases: A large-scale Asian study

Lee, Mei Hsuan and Ahn, Sang Hoon and Chan, Henry L. Y. and Choudhry, Asad and Gani, Rino Alvani and Mohamed, Rosmawati and Ong, Janus P. and Shukla, Akash and Tan, Chee Kiat and Tanwandee, Tawesak and Thuy, Pham Thi Thu and Neo, Boon Leong and Tsang, Venus and Youn, Jin and Singh, Shikha (2022) Contextual and individual factors associated with knowledge, awareness and attitude on liver diseases: A large-scale Asian study. Journal of Viral Hepatitis, 29 (2). pp. 156-170. ISSN 1352-0504, DOI https://doi.org/10.1111/jvh.13636.

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Abstract

There are limited data to provide better understanding of the knowledge/awareness of general population towards liver health in Asia. We sought to identify the knowledge gaps and attitudes towards liver health and liver diseases as well as evaluate associated individual-level and macro-level factors based on contextual analysis. An online survey assessing knowledge, awareness and attitudes towards liver health and disease was conducted among 7500 respondents across 11 countries/territories in Asia. A liver index was created to measure the respondents' knowledge level and the degree of awareness and attitudes. Multilevel logistic regression was performed to identify individual factors and contextual effects that were associated with liver index. The overall liver index (0-100-point scale) was 62.4 with 6 countries/territories' liver indices greater than this. In the multilevel model, the inclusion of geographical information could explain for 9.6% of the variation. Residing in a country/territory with higher HBV prevalence (80% IOR: 1.20-2.79) or higher HCV death rate (80% IOR: 1.35-3.13) increased the individual probability of obtaining a high overall liver index. Individual factors like age, gender, education, household income, disease history and health screening behaviour were also associated with liver index (all p-values<0.001). The overall liver index was positively associated with the two macro-level factors viz. HBV prevalence and HCV death rate. There is a need to formulate policies especially in regions of lower HBV prevalence and HCV death rate to further improve the knowledge, awareness and attitudes of the general public towards liver diseases.

Item Type: Article
Funders: Gilead Sciences
Uncontrolled Keywords: Asia;Liver health;Policy;Public health;Viral hepatitis
Subjects: R Medicine
R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine
R Medicine > RC Internal medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 25 Jul 2022 07:12
Last Modified: 25 Jul 2022 07:12
URI: http://eprints.um.edu.my/id/eprint/33671

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