Chew, Kee Seang and Em, Jun Min and Koay, Zhong Lin and Jalaludin, Muhammad Yazid and Ng, Ruey Terng and Lum, Lucy Chai See and Lee, Way Seah (2021) Low prevalence of infantile functional gastrointestinal disorders (FGIDs) in a multi-ethnic Asian population. Pediatrics & Neonatology, 62 (1). pp. 49-54. ISSN 1875-9572, DOI https://doi.org/10.1016/j.pedneo.2020.08.009.
Full text not available from this repository.Abstract
Background: Functional gastrointestinal disorders (FGIDs) are common in children. The prevalence of FGIDs varies across the world but is unknown in Malaysia. We aimed to investigate the prevalence of FGIDs in healthy Malaysian infants. Methods: This was a cross-sectional study involving healthy infants younger than 12 months of age who attended a well-baby clinic. A universal sampling method was adopted. Children with congenital disorders potentially affecting gastrointestinal functions, chronic debilitating diseases and hypothyroidism were excluded. Rome IV criteria were used to define FGIDs. Results: Of the total 534 infants recruited (54% males), 92% were born at term; 85% had normal birth weight range 2.5-4.0 kg], and the mean (+/- S.D.) age at interview was 6.8 (+/- 3.4) months. Thirty-six percent were breastfed, 29% were formula-fed, and 35% had mixed feeding. Prevalence of infant regurgitation and rumination syndrome was 10.5% and 1.7%, respectively. Prevalence of infant colic was 1.9% (3/160) (infant < 5 months old) while infant dyschezia, functional constipation and diarrhoea were 1.3%, 1.1% and 0.3%, respectively. No subjects fulfilled diagnostic criteria for cyclic vomiting syndrome. Breastfed infants were less likely to regurgitate, after adjustment for age, gender, ethnicity, birth weight and gestation (adjusted OR 0.25 95% CI 0.12-0.54]; p < 0.001). No significant differences among other factors (gender, Malays vs. non-Malays, premature vs. term, and birthweight) were noted for other FGIDs. Conclusion: With the exception of the lower prevalence of infant colic and functional constipation, the prevalence rates of other FGIDs observed in the present study were similar to those published in the literature. Breastfeeding protects against infant regurgitation. Copyright (C) 2020, Taiwan Pediatric Association. Published by Elsevier Taiwan LLC.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Asian; colic; constipation; functional gastrointestinal disorder; infant |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RJ Pediatrics |
| Divisions: | Faculty of Medicine > Paediatrics Department |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 20 Apr 2022 08:32 |
| Last Modified: | 20 Apr 2022 08:32 |
| URI: | http://eprints.um.edu.my/id/eprint/28757 |
Actions (login required)
 |
View Item |
