Letchumanan, Devanthiran and Sok, Sophia P. M. and Ibrahim, Suriani and Nagoor, Noor Hasima and Arshad, Norhafiza Mohd (2021) Plant-based biosynthesis of copper/copper oxide nanoparticles: An update on their applications in biomedicine, mechanisms, and toxicity. Biomolecules, 11 (4). ISSN 2218-273X, DOI https://doi.org/10.3390/biom11040564.
Full text not available from this repository.Abstract
Plants are rich in phytoconstituent biomolecules that served as a good source of medicine. More recently, they have been employed in synthesizing metal/metal oxide nanoparticles (NPs) due to their capping and reducing properties. This green synthesis approach is environmentally friendly and allows the production of the desired NPs in different sizes and shapes by manipulating parameters during the synthesis process. The most commonly used metals and oxides are gold (Au), silver (Ag), and copper (Cu). Among these, Cu is a relatively low-cost metal that is more cost-effective than Au and Ag. In this review, we present an overview and current update of plant-mediated Cu/copper oxide (CuO) NPs, including their synthesis, medicinal applications, and mechanisms. Furthermore, the toxic effects of these NPs and their efficacy compared to commercial NPs are reviewed. This review provides an insight into the potential of developing plant-based Cu/CuO NPs as a therapeutic agent for various diseases in the future.
| Item Type: | Article |
|---|---|
| Funders: | Malaysia Ministry of Higher Education-Fundamental Research Grant Scheme (FP027-2019A), Malaysia Ministry of Higher Education-Fundamental Research Grant Scheme (FRGS/1/2019/STG05/UM/02/5) |
| Uncontrolled Keywords: | Copper; Copper oxide; Green synthesis; Nanoparticles; Biomedicine; Mechanism; Toxicity |
| Subjects: | Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology T Technology > TJ Mechanical engineering and machinery |
| Divisions: | Faculty of Engineering > Department of Mechanical Engineering Faculty of Science Deputy Vice Chancellor (Research & Innovation) Office > Centre for Research in Biotechnology for Agriculture |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 18 Jul 2022 08:14 |
| Last Modified: | 18 Jul 2022 08:14 |
| URI: | http://eprints.um.edu.my/id/eprint/28041 |
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