Kong, Boon Hong and Fung, Shin Yee (2021) Longitudinal assessment of the tiger milk medicinal mushroom, Lignosus rhinocerus (Agaricomycetes), Sclerotium cultivar: Uniformity of bioactive components. International Journal of Medicinal Mushrooms, 23 (10). pp. 61-68. ISSN 1521-9437, DOI https://doi.org/10.1615/IntJMedMushrooms.2021040120.
Full text not available from this repository.Abstract
Traditional use of the tiger milk medicinal mushroom, Lignosus rhinocerus, to treat various illnesses has been recorded for > 4 centuries. Successful cultivation of L. rhinocerus using proprietary solid-state fermentation (SSF) technology by LiGNO Biotech has enabled large-scale production of L. rhinocerus sclerotia (termed L. rhinocerus TM02) and further investigations into its medicinal properties. Pharmacological activities of L. rhinocerus TM02, including its antioxidant, anti-inflammatory, anticancer, and immunomodulatory effects and the bioactive components responsible, have been validated by various scientific studies. In this study, we assessed the consistency of the bioactive components in 11 batches of L. rhinocerus TM02 produced over a 9-year period. The different batches of L. rhinocerus TM02 consisted of stable protein, polysaccharide, and glycoprotein contents, and all tested samples were comparable to the wild type. L. rhinocerus TM02 had greater protein, carbohydrate, and glycoprotein contents, which were mostly bioactive compared to another cultivar from a different cultivation technology (TM-UN). Together with previous scientific validations, L. rhinocerus TM02 produced using SSF cultivation is of optimal quality with high consistent bioactive contents, which can be an appropriate indicator for quality validation of the much sought-after medicinal mushroom, L. rhinocerus.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Malaya (GPF003B-2020), Universiti Malaya (PV014-2019) |
| Uncontrolled Keywords: | Lignosus rhinocerus; Solid-state fermentation technology; Bioactive components; Consistency; Functional foods; Nutraceuticals; Medicinal mushrooms |
| Subjects: | Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 09 Jun 2022 08:09 |
| Last Modified: | 09 Jun 2022 08:09 |
| URI: | http://eprints.um.edu.my/id/eprint/27582 |
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