Prevalence and characteristics of taste disorders in cases of COVID-19: A meta-analysis of 29,349 patients

Saniasiaya, Jeyasakthy and Islam, Md Asiful and Abdullah, Baharudin (2021) Prevalence and characteristics of taste disorders in cases of COVID-19: A meta-analysis of 29,349 patients. Otolaryngology-Head and Neck Surgery, 165 (1). pp. 33-42. ISSN 0194-5998, DOI https://doi.org/10.1177/0194599820981018.

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Abstract

Objective The purpose of this meta-analysis is to assess the pooled prevalence of taste disorders and their subtypes in patients with COVID-19. Data Sources PubMed, Scopus, Web of Science, Embase, and Google Scholar databases were searched to identify studies published between December 1, 2019, and June 23, 2020, without language restrictions. There was no restriction on the study design; therefore, observational studies, clinical trials, and case series were included. In addition, preprints were considered if data of interest were reported. Review Methods Two authors independently screened articles for eligibility. A random effects model was used to estimate the pooled prevalence with 95% CIs. Quality assessment was done with critical appraisal tools of the Joanna Briggs Institute. The robustness of the pooled estimates was checked by subgroup and sensitivity analyses. Results Fifty-nine studies were included (N = 29,349 patients, 64.4% female). The pooled prevalence of taste disorders in patients with COVID-19 was 48.1% (95% CI, 41.3%-54.8%). The prevalence of taste disorders in studies with objective assessments was higher as compared with subjective assessments (59.2% vs 47.3%). The disorders were observed in 55.2% of European patients; 61.0%, North American; 27.1%, Asian; 29.5%, South American; and 25.0%, Australian. Ageusia, hypogeusia, and dysgeusia were detected in 28.0%, 33.5%, and 41.3% of patients with COVID-19. We identified 91.5% of the included studies as high quality. Conclusions The prevalence of taste disorders in patients with COVID-19 was 48.1%. Objective assessments have higher prevalence than subjective assessments. Dysgeusia is the most common subtype, followed by ageusia and hypogeusia.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Coronavirus; COVID-19; Taste; Gustatory; Meta-analysis
Subjects: R Medicine > RF Otorhinolaryngology
Divisions: Faculty of Medicine > Otorhinolaryngology Department
Depositing User: Ms Zaharah Ramly
Date Deposited: 24 May 2022 02:44
Last Modified: 24 May 2022 02:44
URI: http://eprints.um.edu.my/id/eprint/27126

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