Roslan, Amira Adlin and Mohamad, Saharuddin B. and Tayyab, Saad (2021) Docking evaluation of the interaction between green tea active ingredient, l-theanine and human serum albumin. National Academy Science Letters-India, 44 (1). pp. 17-19. ISSN 0250-541X, DOI https://doi.org/10.1007/s40009-020-00949-5.
Full text not available from this repository.Abstract
Interaction of one of the green tea active ingredients, l-theanine with the major transport protein of human blood circulation, human serum albumin (HSA) was investigated using molecular docking analysis. Site-specific docking simulation suggested binding preference of l-theanine to Site 1 of HSA. The binding site is proposed to be a cleft surrounded by both polar and nonpolar residues. l-Theanine binds to the protein through hydrophobic interactions as well as hydrogen bonds formed between Lys residues (195 and 199) of HSA and l-theanine.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Malaya [FG025-17AFR] |
| Uncontrolled Keywords: | l-Theanine; Human serum albumin; Molecular docking; Cluster analysis |
| Subjects: | Q Science > Q Science (General) |
| Divisions: | Faculty of Science |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 11 Apr 2022 06:41 |
| Last Modified: | 11 Apr 2022 06:41 |
| URI: | http://eprints.um.edu.my/id/eprint/26949 |
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