The potential use of volatile biomarkers for malaria diagnosis

Chai, Hwa Chia and Chua, Kek Heng (2021) The potential use of volatile biomarkers for malaria diagnosis. Diagnostics, 11 (12). ISSN 2075-4418, DOI https://doi.org/10.3390/diagnostics11122244.

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Abstract

Pathogens may change the odor and odor-related biting behavior of the vector and host to enhance pathogen transmission. In recent years, volatile biomarker investigations have emerged to identify odors that are differentially and specifically released by pathogens and plants, or the pathogen-infected or even cancer patients. Several studies have reported odors or volatile biomarkers specifically detected from the breath and skin of malaria-infected individuals. This review will discuss the potential use of these odors or volatile biomarkers for the diagnosis of malaria. This approach not only allows for the non-invasive mean of sample collection but also opens up the opportunity to develop a biosensor for malaria diagnosis in low-resource settings.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Malaria diagnosis; Plasmodium; odor; Volatile; Non-invasive
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine
Depositing User: Ms Zaharah Ramly
Date Deposited: 21 Apr 2022 06:41
Last Modified: 21 Apr 2022 06:41
URI: http://eprints.um.edu.my/id/eprint/26868

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